10-methoxy-6-(2-nitrophenyl)-6,12-isopropano-6H,12H,13H-[1]benzopyrano[4,3-d][1,3]-benzooxacin-13-one

Base Information

• Chemical Name: 10-methoxy-6-(2-nitrophenyl)-6,12-isopropano-6H,12H,13H-[1]benzopyrano[4,3-d][1,3]-benzooxacin-13-one
• CAS No.: 1001067-48-6
• Molecular Formula: C₂₇H₂₂N₂O₆
• Molecular Weight: 470.481
• Mol file: 1001067-48-6.mol

Synonyms:10-methoxy-6-(2-nitrophenyl)-6,12-isopropano-6H,12H,13H-[1]benzopyrano[4,3-d][1,3]-benzooxacin-13-one

Chemical Property of 10-methoxy-6-(2-nitrophenyl)-6,12-isopropano-6H,12H,13H-[1]benzopyrano[4,3-d][1,3]-benzooxacin-13-one

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 10-methoxy-6-(2-nitrophenyl)-6,12-isopropano-6H,12H,13H-[1]benzopyrano[4,3-d][1,3]-benzooxacin-13-one

There total 2 articles about 10-methoxy-6-(2-nitrophenyl)-6,12-isopropano-6H,12H,13H-[1]benzopyrano[4,3-d][1,3]-benzooxacin-13-one which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 30.0%

4-hydroxy[1]benzopyran-2-one (1076-38-6,92395-12-5) + 6-methoxy-3,3-dimethyl-2-(2-nitrophenyl)-1,2,3,4-tetrahydroquinolin-4-ol (1001067-44-2) → 10-methoxy-6-(2-nitrophenyl)-6,12-isopropano-6H,12H,13H-[1]benzopyrano[4,3-d][1,3]-benzooxacin-13-one (1001067-48-6)

Guidance literature:

With toluene-4-sulfonic acid; In 1,2-dichloro-ethane; Heating;

DOI:10.1021/ol702482c

Reference yield:

C27H22N2O6 (1001067-53-3) → 10-methoxy-6-(2-nitrophenyl)-6,12-isopropano-6H,12H,13H-[1]benzopyrano[4,3-d][1,3]-benzooxacin-13-one (1001067-48-6)

Guidance literature:

In acetonitrile; at 60 ℃;

DOI:10.1021/ol702482c

Reference yield: 80.0%

diazomethane (186581-53-3,908094-01-9,334-88-3) + 10-methoxy-6-(2-nitrophenyl)-6,12-isopropano-6H,12H,13H-[1]benzopyrano[4,3-d][1,3]-benzooxacin-13-one (1001067-48-6) → C28H24N2O6 (1001067-52-2)

Guidance literature:

10-methoxy-6-(2-nitrophenyl)-6,12-isopropano-6H,12H,13H-[1]benzopyrano[4,3-d][1,3]-benzooxacin-13-one; In acetonitrile; UV-irradiation;

diazomethane; In acetonitrile; Further stages.;

DOI:10.1021/ol702482c

upstream raw materials:

4-hydroxy[1]benzopyran-2-one

6-methoxy-3,3-dimethyl-2-(2-nitrophenyl)-1,2,3,4-tetrahydroquinolin-4-ol

C₂₇H₂₂N₂O₆

Downstream raw materials:

C₂₈H₂₄N₂O₆

C₂₇H₂₂N₂O₆

10-methoxy-7-methyl-6-(2-nitrophenyl)-6,12-isopropano-6H,12H,13H-[1]benzopyrano[4,3-d][1,3]-benzooxacin-13-one