2,6-dimethyl-4-(trifluoromethyl)benzeneamine hydrochloride

Base Information

• Chemical Name: 2,6-dimethyl-4-(trifluoromethyl)benzeneamine hydrochloride
• CAS No.: 1194046-26-8
• Molecular Formula: C₉H₁₀F₃N*ClH
• Molecular Weight: 225.641
• Mol file: 1194046-26-8.mol

Synonyms:2,6-dimethyl-4-(trifluoromethyl)benzeneamine hydrochloride

Chemical Property of 2,6-dimethyl-4-(trifluoromethyl)benzeneamine hydrochloride

Chemical Property:

Purity/Quality:

99% ^*data from raw suppliers

2,6-DIMETHYL-4-(TRIFLUOROMETHYL)ANILINE HYDROCHLORIDE 95.00% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 2,6-dimethyl-4-(trifluoromethyl)benzeneamine hydrochloride

There total 1 articles about 2,6-dimethyl-4-(trifluoromethyl)benzeneamine hydrochloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

Trimethylboroxine (823-96-1) + 2,6-dibromo-4-trifluoromethylaniline (72678-19-4) → 2,6-dimethyl-4-(trifluoromethyl)benzeneamine hydrochloride (1194046-26-8)

Guidance literature:

Trimethylboroxine; 2,6-dibromo-4-trifluoromethylaniline; With tetrakis(triphenylphosphine) palladium⁽⁰⁾; potassium carbonate; In N,N-dimethyl-formamide; at 90 ℃; for 17h; Inert atmosphere;

With hydrogenchloride; In 1,4-dioxane; water; at 0 ℃; for 0.166667h;

DOI:10.1021/jm801416q

Reference yield:

bis(trichloromethyl) carbonate (32315-10-9) + 2,6-dimethyl-4-(trifluoromethyl)benzeneamine hydrochloride (1194046-26-8) → 2,6-dimethyl-4-(trifluoromethyl)phenyl isocyanate (1123813-53-5)

Guidance literature:

With N-ethyl-N,N-diisopropylamine; In dichloromethane;

DOI:10.1021/jm801416q

upstream raw materials:

Trimethylboroxine

2,6-dibromo-4-trifluoromethylaniline

Downstream raw materials:

2,6-dimethyl-4-(trifluoromethyl)phenyl isocyanate