cis-4-dimethylamino-1-{2-[α-methoxy-(phenylmethyl)]phenyl}cyclohexanol

Base Information

• Chemical Name: cis-4-dimethylamino-1-{2-[α-methoxy-(phenylmethyl)]phenyl}cyclohexanol
• CAS No.: 78263-18-0
• Molecular Formula: C₂₂H₂₉NO₂
• Molecular Weight: 339.478
• Mol file: 78263-18-0.mol

Synonyms:cis-4-dimethylamino-1-{2-[α-methoxy-(phenylmethyl)]phenyl}cyclohexanol

Chemical Property of cis-4-dimethylamino-1-{2-[α-methoxy-(phenylmethyl)]phenyl}cyclohexanol

Chemical Property:

Purity/Quality:

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MSDS Files:

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Technology Process of cis-4-dimethylamino-1-{2-[α-methoxy-(phenylmethyl)]phenyl}cyclohexanol

There total 1 articles about cis-4-dimethylamino-1-{2-[α-methoxy-(phenylmethyl)]phenyl}cyclohexanol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 32.4%

1-bromo-2-[methoxy(phenyl)methyl]-benzene (59142-71-1) + 4-(dimethylamino)cyclohexanone (40594-34-1) → cis-4-dimethylamino-1-{2-[α-methoxy-(phenylmethyl)]phenyl}cyclohexanol (78263-18-0)

Guidance literature:

In tetrahydrofuran; hexane; water;

Reference yield:

cis-4-dimethylamino-1-{2-[α-methoxy-(phenylmethyl)]phenyl}cyclohexanol (78263-18-0) → cis-4-dimethylamino-3'-phenylspiro[cyclohexane-1,1'(3'H)-isobenzofuran] (78262-65-4,78262-89-2)

Guidance literature:

With hydrogenchloride; sodium hydroxide; acetic acid; In hexane; water;

upstream raw materials:

1-bromo-2-[methoxy(phenyl)methyl]-benzene

4-(dimethylamino)cyclohexanone

Downstream raw materials:

cis-4-dimethylamino-3'-phenylspiro[cyclohexane-1,1'(3'H)-isobenzofuran]