3-Phenoxybenzylamine hydrochloride

Base Information

• Chemical Name: 3-Phenoxybenzylamine hydrochloride
• CAS No.: 376637-85-3
• Molecular Formula: C13H14ClNO
• Molecular Weight: 235.713
• Hs Code.: 2922290090
• Mol file: 376637-85-3.mol

Synonyms:Benzenemethanamine,3-phenoxy-, hydrochloride (9CI);3-Phenoxybenzylamine hydrochloride;

Chemical Property of 3-Phenoxybenzylamine hydrochloride

Chemical Property:

• Vapor Pressure: 0.000277mmHg at 25°C
• Melting Point: 185.5 °C
• Refractive Index: 1.594
• Boiling Point: 354.4 °C at 760 mmHg
• Flash Point: 168.1 °C
• PSA: 35.25000
• Density: 1.106g/cm³
• LogP: 4.43990

Purity/Quality:

98%Min ^*data from raw suppliers

(3-Phenoxybenzyl)amineHydrochloride ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 3-Phenoxybenzylamine hydrochloride

There total 2 articles about 3-Phenoxybenzylamine hydrochloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

3-Phenoxybenzaldehyde (39515-51-0) → 3-phenoxybenzylamine hydrochloric acid salt (376637-85-3)

Guidance literature:

3-Phenoxybenzaldehyde; With hydroxylamine hydrochloride; In ethanol; water; at 20 ℃;

With hydrogenchloride; hydrogen; palladium 10% on activated carbon; In ethanol; water; for 6h; under 760.051 Torr;

Reference yield:

3-phenoxybenzonitrile (50789-45-2) → 3-phenoxybenzylamine hydrochloric acid salt (376637-85-3)

Guidance literature:

3-phenoxybenzonitrile; With [ruthenium(II)(η⁶-1-methyl-4-isopropyl-benzene)(chloride)(μ-chloride)]₂; In isopropyl alcohol; at 200 ℃; under 75007.5 Torr;

With hydrogenchloride; In 1,4-dioxane; hexane;

DOI:10.1055/s-0036-1589096

Reference yield: 55.0%

3-phenoxybenzylamine hydrochloric acid salt (376637-85-3) + 1-(4-methoxyphenyl)pentane-1,4-dione (2108-54-5) → 2-(4-methoxyphenyl)-5-methyl-1-(3-phenoxybenzyl)-1H-pyrrole (376637-83-1)

Guidance literature:

With p-toluenesulfonic acid monohydrate; In toluene;

upstream raw materials:

3-Phenoxybenzaldehyde

3-phenoxybenzonitrile

Downstream raw materials:

2-(4-methoxyphenyl)-5-methyl-1-(3-phenoxybenzyl)-1H-pyrrole

N-(3-phenoxyphenyl)methyl-2-amino-6-methylnicotinic acid amide

N-(3-phenoxyphenyl)methyl-2,6-diaminonicotinic acid amide

Refernces

• 1、 -. "COMPOSITION FOR AGRICULTURAL USE FOR CONTROLLING OR PREVENTING PLANT DISEASES CAUSED BY PLANT PATHOGENS". Page/Page column 261-262. . Retrieved 2010/11/19.