5-Bromopyridine-2-carboxamide

Base Information

Chemical Name:5-Bromopyridine-2-carboxamide
CAS No.:90145-48-5
Molecular Formula:C6H5BrN2O
Molecular Weight:201.023
Hs Code.:2933399090
European Community (EC) Number:692-030-1
DSSTox Substance ID:DTXSID90352742
Wikidata:Q72511923
Mol file:90145-48-5.mol

Synonyms:5-Bromopyridine-2-carboxamide;90145-48-5;5-BROMOPICOLINAMIDE;MFCD04066715;5-BROMOPYRIDINE-2-CARBOXAMIDE 97%5-BROMOPICOLINAMIDE;SCHEMBL157129;DTXSID90352742;IPWPEOLXILHOLV-UHFFFAOYSA-N;BCP29826;AKOS002354397;AC-5076;CS-W022338;FS-2661;SB77869;5-bromo-pyridine-2-carboxylic acid amide;BL003043;SY064801;FT-0650919;A19281;EN300-7050647;J-517200;Z1065600734;5-Bromopicolinamide;5-Bromo-2-carbamoylpyridine;2-Pyridinecarboxamide,5-bromo

Suppliers and Price of 5-Bromopyridine-2-carboxamide

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
5-Bromopicolinamide
500mg
$ 85.00

SynQuest Laboratories
5-Bromopyridine-2-carboxamide 97.0%
250 mg
$ 31.00

SynQuest Laboratories
5-Bromopyridine-2-carboxamide 97.0%
1 g
$ 68.00

SynQuest Laboratories
5-Bromopyridine-2-carboxamide 97.0%
5 g
$ 232.00

Matrix Scientific
5-Bromopyridine-2-carboxamide 95+%
5g
$ 1298.00

Matrix Scientific
5-Bromopyridine-2-carboxamide 95+%
1g
$ 462.00

Labseeker
2-Pyridinecarboxamide,5-bromo 95
5g
$ 431.00

Crysdot
5-Bromopyridine-2-carboxamide 98%
10g
$ 253.00

Chemenu
5-bromopyridine-2-carboxamide 98%
10g
$ 239.00

Biosynth Carbosynth
5-Bromopicolinamide
10 g
$ 575.00

Total 44 raw suppliers

Chemical Property of 5-Bromopyridine-2-carboxamide

Chemical Property:

Vapor Pressure:0.000181mmHg at 25°C
Melting Point:218-220°C
Refractive Index:1.613
Boiling Point:329.1 °C at 760 mmHg
Flash Point:152.8 °C
PSA：55.98000
Density:1.71g/cm³
LogP:1.64330
Storage Temp.:Keep Cold
XLogP3:0.8
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:1
Exact Mass:199.95853
Heavy Atom Count:10
Complexity:140

Purity/Quality:

99%, ^*data from raw suppliers

5-Bromopicolinamide ^*data from reagent suppliers

Safty Information:

Pictogram(s): Xi
Hazard Codes:Xi

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CC(=NC=C1Br)C(=O)N

Technology Process of 5-Bromopyridine-2-carboxamide

There total 2 articles about 5-Bromopyridine-2-carboxamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 92.4%

: 30766-11-1
5-bromoisonicotinic acid

: 90145-48-5
5-bromo-2-pyridinecarboxamide

Guidance literature:: 5-bromoisonicotinic acid; With thionyl chloride; N,N-dimethyl-formamide; In dichloromethane; at 80 ℃; for 1h;

With ammonium hydroxide; In dichloromethane; at 20 ℃; for 1.5h;

Reference yield:

: 90145-48-5
5-bromo-2-pyridinecarboxamide

Guidance literature:: With dihydrogen peroxide; potassium carbonate; In water; dimethyl sulfoxide; at 20 ℃; Cooling with ice;

Reference yield: 11.0%

: 90145-48-5
5-bromo-2-pyridinecarboxamide

: methyl 3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-5-(4-(4-(trifluoromethyl)phenyl)-1H-1,2,3-triazol-1-yl)benzoate

: methyl 3-(6-carbamoylpyridin-3-yl)-5-(4-(4-(trifluoromethyl)phenyl)-1H-1,2,3-triazol-1-yl)benzoate

Guidance literature:: With tetrakis(triphenylphosphine) palladium⁽⁰⁾; sodium carbonate; In water; N,N-dimethyl-formamide; at 40 - 120 ℃; for 1h; Inert atmosphere;
DOI:10.1021/acs.jmedchem.8b00168