(S)-methyl 5-(4-(benzyloxy)phenyl)-3,4-dihydro-2H-pyrrole-2-carboxylate

Base Information

Chemical Name:(S)-methyl 5-(4-(benzyloxy)phenyl)-3,4-dihydro-2H-pyrrole-2-carboxylate
CAS No.:934240-38-7
Molecular Formula:C₁₉H₁₉NO₃
Molecular Weight:309.365
Hs Code.:
Mol file:934240-38-7.mol

Synonyms:(S)-methyl-5-(4-(benzyloxy)phenyl)-3,4-dihydro-2H-pyrrole-2-carboxylate

Suppliers and Price of (S)-methyl 5-(4-(benzyloxy)phenyl)-3,4-dihydro-2H-pyrrole-2-carboxylate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Total 3 raw suppliers

Chemical Property of (S)-methyl 5-(4-(benzyloxy)phenyl)-3,4-dihydro-2H-pyrrole-2-carboxylate

Chemical Property:

Boiling Point:435.5±45.0 °C(Predicted)
PKA:6.03±0.40(Predicted)
Density:1.15±0.1 g/cm3(Predicted)

Purity/Quality:: 99.9% ^*data from raw suppliers

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Technology Process of (S)-methyl 5-(4-(benzyloxy)phenyl)-3,4-dihydro-2H-pyrrole-2-carboxylate

There total 6 articles about (S)-methyl 5-(4-(benzyloxy)phenyl)-3,4-dihydro-2H-pyrrole-2-carboxylate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 93.0%

: tert-butyl (S)-4-(3-(4-(benzyloxy)phenyl)-3-oxopropyl)-5-oxooxazolidine-3-carboxylate

: 934240-38-7
(S)-methyl-5-(4-(benzyloxy)phenyl)-3,4-dihydro-2H-pyrrole-2-carboxylate

Guidance literature:: With methanesulfonic acid; In methanol; at 20 ℃; for 6h; Reagent/catalyst; Solvent; Temperature;

Reference yield: 92.0%

: 934240-37-6
(S)-methyl 5-(4-(benzyloxy)phenyl)-2-((tert-butoxycarbonyl)amino)-5-oxopentanoate

: 934240-38-7
(S)-methyl-5-(4-(benzyloxy)phenyl)-3,4-dihydro-2H-pyrrole-2-carboxylate

Guidance literature:: With ammonium hydroxide; methanesulfonic acid; In tetrahydrofuran; water; acetonitrile; at 130 ℃; for 0.0216667h; Temperature; Reagent/catalyst; Solvent; Flow reactor;

Reference yield:

: 108963-96-8
(S)-1-tert-butoxycarbonyl-5-methoxycarbonyl-pyrrolidin-2-one

: 934240-38-7
(S)-methyl-5-(4-(benzyloxy)phenyl)-3,4-dihydro-2H-pyrrole-2-carboxylate

Guidance literature:: Multi-step reaction with 2 steps

1.1: magnesium; iodine / tetrahydrofuran / 1.75 h / Inert atmosphere; Reflux

1.2: 2.25 h / -75 - -65 °C / Inert atmosphere

2.1: trifluoroacetic acid / dichloromethane / 2.75 h / 20 °C / Inert atmosphere; Cooling with ice

With iodine; magnesium; trifluoroacetic acid; In tetrahydrofuran; dichloromethane;