2-(trimethylsilyl)ethyl 2,3,4-tri-O-benzyl-α-L-fucopyranosyl-(1->3)-2,4,6-tri-O-acetyl-β-D-galactopyranosyl-(1->6)-2,3,4-tri-O-benzoyl-β-D-galactopyranoside

Base Information

Chemical Name:2-(trimethylsilyl)ethyl 2,3,4-tri-O-benzyl-α-L-fucopyranosyl-(1->3)-2,4,6-tri-O-acetyl-β-D-galactopyranosyl-(1->6)-2,3,4-tri-O-benzoyl-β-D-galactopyranoside
CAS No.:231616-50-5
Molecular Formula:C₇₁H₈₀O₂₁Si
Molecular Weight:1297.49
Hs Code.:

2-(trimethylsilyl)ethyl 2,3,4-tri-O-benzyl-α-L-fucopyranosyl-(1->3)-2,4,6-tri-O-acetyl-β-D-galactopyranosyl-(1->6)-2,3,4-tri-O-benzoyl-β-D-galactopyranoside

Synonyms:2-(trimethylsilyl)ethyl 2,3,4-tri-O-benzyl-α-L-fucopyranosyl-(1->3)-2,4,6-tri-O-acetyl-β-D-galactopyranosyl-(1->6)-2,3,4-tri-O-benzoyl-β-D-galactopyranoside

Suppliers and Price of 2-(trimethylsilyl)ethyl 2,3,4-tri-O-benzyl-α-L-fucopyranosyl-(1->3)-2,4,6-tri-O-acetyl-β-D-galactopyranosyl-(1->6)-2,3,4-tri-O-benzoyl-β-D-galactopyranoside

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of 2-(trimethylsilyl)ethyl 2,3,4-tri-O-benzyl-α-L-fucopyranosyl-(1->3)-2,4,6-tri-O-acetyl-β-D-galactopyranosyl-(1->6)-2,3,4-tri-O-benzoyl-β-D-galactopyranoside

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of 2-(trimethylsilyl)ethyl 2,3,4-tri-O-benzyl-α-L-fucopyranosyl-(1->3)-2,4,6-tri-O-acetyl-β-D-galactopyranosyl-(1->6)-2,3,4-tri-O-benzoyl-β-D-galactopyranoside

There total 12 articles about 2-(trimethylsilyl)ethyl 2,3,4-tri-O-benzyl-α-L-fucopyranosyl-(1->3)-2,4,6-tri-O-acetyl-β-D-galactopyranosyl-(1->6)-2,3,4-tri-O-benzoyl-β-D-galactopyranoside which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 89.0%

: 107802-80-2
(2S,3R,4R,5S,6R)-3,4,5-Tris-benzyloxy-2-methyl-6-methylsulfanyl-tetrahydro-pyran

: 231616-48-1
2-(trimethylsilyl)ethyl 2,4,6-tri-O-acetyl-β-D-galactopyranosyl-(1->6)-2,3,4-tri-O-benzoyl-β-D-galactopyranoside

: 231616-50-5
2-(trimethylsilyl)ethyl 2,3,4-tri-O-benzyl-α-L-fucopyranosyl-(1->3)-2,4,6-tri-O-acetyl-β-D-galactopyranosyl-(1->6)-2,3,4-tri-O-benzoyl-β-D-galactopyranoside

Guidance literature:: With 4 A molecular sieve; dimethyl-(methylthio)-sulphonium trifluoromethanesulphonate; In dichloromethane; at 0 ℃; for 5h;
DOI:10.1016/S0008-6215(99)00027-0

Reference yield:

: 16758-34-2
1-thiophenyl-β-D-galactopyranoside

: 231616-50-5
2-(trimethylsilyl)ethyl 2,3,4-tri-O-benzyl-α-L-fucopyranosyl-(1->3)-2,4,6-tri-O-acetyl-β-D-galactopyranosyl-(1->6)-2,3,4-tri-O-benzoyl-β-D-galactopyranoside

Guidance literature:: Multi-step reaction with 8 steps

1: 1.) dibutyltin oxide; 2.) Bu₄NBr / 1.) benzene, reflux, 5 h; 2.) 5 h

2: imidazole / dimethylformamide / 3 h / Ambient temperature

3: pyridine / 4 h / 0 °C

4: 58 percent / 4 Angsroem molecular sieves, NIS, TfOH / CH₂Cl₂ / 0.33 h / 0 °C

5: 75 percent / AcOH / tetrahydrofuran; H₂O / 3 h / 50 °C

6: pyridine / 2 h / Ambient temperature

7: H₂, AcOH / 10 percent Pd/C / methanol / 2 h / Ambient temperature

8: 89 percent / 4 Angstroem molecular sieves, dimethyl(methylthio)sulfonium triflate / CH₂Cl₂ / 5 h / 0 °C

With pyridine; 1H-imidazole; N-iodo-succinimide; trifluorormethanesulfonic acid; 4 A molecular sieve; tetrabutylammomium bromide; hydrogen; di(n-butyl)tin oxide; acetic acid; dimethyl-(methylthio)-sulphonium trifluoromethanesulphonate; palladium on activated charcoal; In tetrahydrofuran; methanol; dichloromethane; water; N,N-dimethyl-formamide;
DOI:10.1016/S0008-6215(99)00027-0

Reference yield:

: 117252-95-6
2-(trimethylsilyl)ethyl β-D-galactopyranoside

: 231616-50-5
2-(trimethylsilyl)ethyl 2,3,4-tri-O-benzyl-α-L-fucopyranosyl-(1->3)-2,4,6-tri-O-acetyl-β-D-galactopyranosyl-(1->6)-2,3,4-tri-O-benzoyl-β-D-galactopyranoside

Guidance literature:: Multi-step reaction with 8 steps

1: 83.1 percent / imidazole / dimethylformamide / 6 h / Ambient temperature

2: pyridine / 4 h / 0 °C

3: 89 percent / 80 percent AcOH / 3 h / 40 °C

4: 58 percent / 4 Angsroem molecular sieves, NIS, TfOH / CH₂Cl₂ / 0.33 h / 0 °C

5: 75 percent / AcOH / tetrahydrofuran; H₂O / 3 h / 50 °C

6: pyridine / 2 h / Ambient temperature

7: H₂, AcOH / 10 percent Pd/C / methanol / 2 h / Ambient temperature

8: 89 percent / 4 Angstroem molecular sieves, dimethyl(methylthio)sulfonium triflate / CH₂Cl₂ / 5 h / 0 °C

With pyridine; 1H-imidazole; N-iodo-succinimide; trifluorormethanesulfonic acid; 4 A molecular sieve; hydrogen; acetic acid; dimethyl-(methylthio)-sulphonium trifluoromethanesulphonate; palladium on activated charcoal; In tetrahydrofuran; methanol; dichloromethane; water; N,N-dimethyl-formamide;
DOI:10.1016/S0008-6215(99)00027-0