5-(2-furyl)-1H-pyrazole-3-carboxylic acid

Base Information

Chemical Name:5-(2-furyl)-1H-pyrazole-3-carboxylic acid
CAS No.:116153-81-2
Molecular Formula:C8H6N2O3
Molecular Weight:178.14
Hs Code.:29331990
European Community (EC) Number:681-175-6
Nikkaji Number:J3.149.701I
Wikidata:Q106902787
ChEMBL ID:CHEMBL1502137
Mol file:116153-81-2.mol

Synonyms:116153-81-2;5-(2-furyl)-1H-pyrazole-3-carboxylic acid;5-(furan-2-yl)-1H-pyrazole-3-carboxylic acid;3-(furan-2-yl)-1H-pyrazole-5-carboxylic acid;5-Furan-2-yl-2H-pyrazole-3-carboxylic acid;890006-97-0;CHEMBL1502137;MFCD05170057;3-(2-furyl)-1h-pyrazole-5-carboxylic acid;5-(Furan-2-yl)-2H-pyrazole-3-carboxylic acid;1H-Pyrazole-3-carboxylic acid, 5-(2-furanyl)-;5-(2-furyl)pyrazole-3-carboxylic acid;SMR000010657;5-Fur-2-yl-1H-pyrazole-3-carboxylic acid;MLS000074734;SCHEMBL570055;SCHEMBL644425;HMS2407L18;BBL011723;BDBM50501669;MFCD03030184;STK346967;AKOS000146846;AKOS000271377;BS-3281;SB61067;WAY-337227;5-(2-furyl)-2H-pyrazole-3-carboxylic acid;BB 0219095;CS-0312722;FT-0732800;5-(Fur-2-yl)-1H-pyrazole-3-carboxylic acid;5-furan-2-yl-2 h-pyrazole-3-carboxylic acid;EN300-30679;D94448;2H-Pyrazole-3-carboxylic acid, 5-furan-2-yl-;SR-01000595326;SR-01000595326-1;W-204893;5-(2-Furyl)-1H-pyrazole-3-carboxylic acid, AldrichCPR;5-Furan-2-yl-2H-pyrazole-3-carboxylic acid, AldrichCPR;F0918-7944;F2169-0893;Z317046484;7O4

Suppliers and Price of 5-(2-furyl)-1H-pyrazole-3-carboxylic acid

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
5-(2-Furyl)-1h-pyrazole-3-carboxylicacid
1g
$ 200.00

SynQuest Laboratories
5-(Fur-2-yl)-1H-pyrazole-3-carboxylic acid 97%
5 g
$ 224.00

SynQuest Laboratories
5-(Fur-2-yl)-1H-pyrazole-3-carboxylic acid 97%
1 g
$ 120.00

Matrix Scientific
5-Furan-2-yl-2H-pyrazole-3-carboxylic acid
1g
$ 378.00

Frontier Specialty Chemicals
5-(2-Furyl)-1H-pyrazole-3-carboxylicacid 97%
1g
$ 94.00

Frontier Specialty Chemicals
5-(2-Furyl)-1H-pyrazole-3-carboxylicacid 97%
5g
$ 391.00

Crysdot
5-(Furan-2-yl)-4H-pyrazole-3-carboxylicacid 95+%
10g
$ 491.00

Chemenu
5-Furan-2-yl-2H-pyrazole-3-carboxylicacid 95%
10g
$ 464.00

Apolloscientific
5-(Fur-2-yl)-1H-pyrazole-3-carboxylic acid 97%
1g
$ 102.00

Apolloscientific
5-(Fur-2-yl)-1H-pyrazole-3-carboxylic acid 97%
5g
$ 189.00

Total 17 raw suppliers

Chemical Property of 5-(2-furyl)-1H-pyrazole-3-carboxylic acid

Chemical Property:

Vapor Pressure:2.45E-10mmHg at 25°C
Melting Point:216-218 °C
Refractive Index:1.617
Boiling Point:488 °C at 760 mmHg
Flash Point:248.9 °C
PSA：79.12000
Density:1.465 g/cm³
LogP:1.36790
XLogP3:0.8
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:2
Exact Mass:178.03784206
Heavy Atom Count:13
Complexity:210

Purity/Quality:

97% ^*data from raw suppliers

5-(2-Furyl)-1h-pyrazole-3-carboxylicacid ^*data from reagent suppliers

Safty Information:

Pictogram(s): Xn
Hazard Codes:Xn
Statements: 22-36/37/38-20/21
Safety Statements: 22-26-36/37/39

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=COC(=C1)C2=CC(=NN2)C(=O)O

Technology Process of 5-(2-furyl)-1H-pyrazole-3-carboxylic acid

There total 7 articles about 5-(2-furyl)-1H-pyrazole-3-carboxylic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 73.0%

: 904733-74-0,197507-85-0
5-(furan-2-yl)-3-(trifluoromethyl)-1H-pyrazole

: 116153-81-2
5-(furan-2-yl)-1H-pyrazole-3-carboxylic acid

Guidance literature:: With water; sodium hydroxide; In ethanol; at 120 ℃; for 1h; Microwave irradiation; Sealed tube;
DOI:10.1016/j.tet.2012.10.034

Reference yield:

: 326-90-9
4,4,4-trifluoro-1-(2-furanyl)-1,3-butanedione

: 116153-81-2
5-(furan-2-yl)-1H-pyrazole-3-carboxylic acid

Guidance literature:: Multi-step reaction with 2 steps

1.1: hydrazine hydrate / ethanol / Reflux

1.2: 0.02 h / Reflux

2.1: sodium hydroxide; water / ethanol / 1 h / 120 °C / Microwave irradiation; Sealed tube

With hydrazine hydrate; water; sodium hydroxide; In ethanol;
DOI:10.1016/j.tet.2012.10.034