2-[(1S)-1-[[(1,1-dimethylethoxy)carbonyl]amino]-2-((triphenylmethyl)thio)ethyl]-2-(4S)-oxazolinemethyl ester

Base Information

• Chemical Name: 2-[(1S)-1-[[(1,1-dimethylethoxy)carbonyl]amino]-2-((triphenylmethyl)thio)ethyl]-2-(4S)-oxazolinemethyl ester
• CAS No.: 940950-95-8
• Molecular Formula: C₃₁H₃₄N₂O₅S
• Molecular Weight: 546.687

Synonyms:2-[(1S)-1-[[(1,1-dimethylethoxy)carbonyl]amino]-2-((triphenylmethyl)thio)ethyl]-2-(4S)-oxazolinemethyl ester

Chemical Property of 2-[(1S)-1-[[(1,1-dimethylethoxy)carbonyl]amino]-2-((triphenylmethyl)thio)ethyl]-2-(4S)-oxazolinemethyl ester

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 2-[(1S)-1-[[(1,1-dimethylethoxy)carbonyl]amino]-2-((triphenylmethyl)thio)ethyl]-2-(4S)-oxazolinemethyl ester

There total 4 articles about 2-[(1S)-1-[[(1,1-dimethylethoxy)carbonyl]amino]-2-((triphenylmethyl)thio)ethyl]-2-(4S)-oxazolinemethyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 97.0%

methyl (2S,2'R)-2-azido-3-(N-Boc-S-trityl-cysteinyloxy)propionate (940950-89-0) → 2-[(1S)-1-[[(1,1-dimethylethoxy)carbonyl]amino]-2-((triphenylmethyl)thio)ethyl]-2-(4S)-oxazolinemethyl ester (940950-95-8)

Guidance literature:

With triphenylphosphine; In tetrahydrofuran; at -20 - 40 ℃; for 6.25h; chemoselective reaction; Inert atmosphere;

DOI:10.1002/ejoc.201300160

Reference yield: 85.0%

N-Boc-Cys(Tr)-Ser(TES)-OMe → 2-[(1S)-1-[[(1,1-dimethylethoxy)carbonyl]amino]-2-((triphenylmethyl)thio)ethyl]-2-(4S)-oxazolinemethyl ester (940950-95-8)

Guidance literature:

With diethylamino-sulfur trifluoride; In dichloromethane; at -78 - 20 ℃; Reagent/catalyst;

DOI:10.1021/jo5016695

Reference yield: 79.0%

methyl N-(tert-butoxycarbonyl)-S-trityl-L-cysteinyl-L-serinate (1128085-78-8) → 2-[(1S)-1-[[(1,1-dimethylethoxy)carbonyl]amino]-2-((triphenylmethyl)thio)ethyl]-2-(4S)-oxazolinemethyl ester (940950-95-8)

Guidance literature:

With diethylamino-sulfur trifluoride; In dichloromethane; at -78 ℃; Reagent/catalyst;

DOI:10.1021/jo5016695

upstream raw materials:

methyl (2S,2'R)-2-azido-3-(N-Boc-S-trityl-cysteinyloxy)propionate

methyl N-(tert-butoxycarbonyl)-S-trityl-L-cysteinyl-L-serinate

N-tert-butyloxycarbonyl-S-trityl-L-cysteine

Downstream raw materials:

methyl (R)-2-(1-((tert-butoxycarbonyl)amino)-2-(tritylthio)ethyl)oxazole-4-carboxylate

Post a RFQ

Cas No.:

Product Name:

Quantity:

Please select Metric Ton KG G Pound L ML

Email:

Company name:

Valid Period:

Detailed Requirements:

• Sample
• MOQ
• GMP
• FDA
• Price
  FOB CIF CFR EXW
• Urgent purchase

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

Remove

Submit

1

What can I do for you?
Get Best Price

Get Best Price for 940950-95-8 2-[(1S)-1-[[(1,1-dimethylethoxy)carbonyl]amino]-2-((triphenylmethyl)thio)ethyl]-2-(4S)-oxazolinemethyl ester

Send

Send

Metric Ton KG G Pound L ML

Send

Send