4-Cyclohexyl-1-(4-methoxy-phenyl)-2-oxo-pyrrolidine-3-carboxylic acid (1S,2R,3R,4S)-4,7,7-trimethyl-3-naphthalen-1-yl-bicyclo[2.2.1]hept-2-yl ester

Base Information

Chemical Name:4-Cyclohexyl-1-(4-methoxy-phenyl)-2-oxo-pyrrolidine-3-carboxylic acid (1S,2R,3R,4S)-4,7,7-trimethyl-3-naphthalen-1-yl-bicyclo[2.2.1]hept-2-yl ester
CAS No.:210585-56-1
Molecular Formula:C₃₈H₄₅NO₄
Molecular Weight:579.78
Hs Code.:

Synonyms:4-Cyclohexyl-1-(4-methoxy-phenyl)-2-oxo-pyrrolidine-3-carboxylic acid (1S,2R,3R,4S)-4,7,7-trimethyl-3-naphthalen-1-yl-bicyclo[2.2.1]hept-2-yl ester

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of 4-Cyclohexyl-1-(4-methoxy-phenyl)-2-oxo-pyrrolidine-3-carboxylic acid (1S,2R,3R,4S)-4,7,7-trimethyl-3-naphthalen-1-yl-bicyclo[2.2.1]hept-2-yl ester

Chemical Property:

Purity/Quality:: 98% ^*data from raw suppliers

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Technology Process of 4-Cyclohexyl-1-(4-methoxy-phenyl)-2-oxo-pyrrolidine-3-carboxylic acid (1S,2R,3R,4S)-4,7,7-trimethyl-3-naphthalen-1-yl-bicyclo[2.2.1]hept-2-yl ester

There total 4 articles about 4-Cyclohexyl-1-(4-methoxy-phenyl)-2-oxo-pyrrolidine-3-carboxylic acid (1S,2R,3R,4S)-4,7,7-trimethyl-3-naphthalen-1-yl-bicyclo[2.2.1]hept-2-yl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: N-(2-cyclohexylethyl)-N-(4-methoxyphenyl)amine

: 210585-56-1
4-Cyclohexyl-1-(4-methoxy-phenyl)-2-oxo-pyrrolidine-3-carboxylic acid (1S,2R,3R,4S)-4,7,7-trimethyl-3-naphthalen-1-yl-bicyclo[2.2.1]hept-2-yl ester

Guidance literature:: Multi-step reaction with 4 steps

3: MsN₃, KH / tetrahydrofuran

4: Rh₂(OAc)4 / CH₂Cl₂ / Heating

With dirhodium tetraacetate; potassium hydride; Methanesulfonyl azide; In tetrahydrofuran; dichloromethane;
DOI:10.1016/0040-4039(95)02115-9

Reference yield:

: 210585-22-1
N-(2-Cyclohexyl-ethyl)-N-(4-methoxy-phenyl)-malonamic acid

: 210585-56-1
4-Cyclohexyl-1-(4-methoxy-phenyl)-2-oxo-pyrrolidine-3-carboxylic acid (1S,2R,3R,4S)-4,7,7-trimethyl-3-naphthalen-1-yl-bicyclo[2.2.1]hept-2-yl ester

Guidance literature:: Multi-step reaction with 3 steps

2: MsN₃, KH / tetrahydrofuran

3: Rh₂(OAc)4 / CH₂Cl₂ / Heating

With dirhodium tetraacetate; potassium hydride; Methanesulfonyl azide; In tetrahydrofuran; dichloromethane;
DOI:10.1016/0040-4039(95)02115-9

Reference yield:

: 210585-31-2
N-(2-Cyclohexyl-ethyl)-N-(4-methoxy-phenyl)-malonamic acid (1S,2R,3R,4S)-4,7,7-trimethyl-3-naphthalen-1-yl-bicyclo[2.2.1]hept-2-yl ester

: 210585-56-1
4-Cyclohexyl-1-(4-methoxy-phenyl)-2-oxo-pyrrolidine-3-carboxylic acid (1S,2R,3R,4S)-4,7,7-trimethyl-3-naphthalen-1-yl-bicyclo[2.2.1]hept-2-yl ester

Guidance literature:: Multi-step reaction with 2 steps

1: MsN₃, KH / tetrahydrofuran

2: Rh₂(OAc)4 / CH₂Cl₂ / Heating

With dirhodium tetraacetate; potassium hydride; Methanesulfonyl azide; In tetrahydrofuran; dichloromethane;
DOI:10.1016/0040-4039(95)02115-9