C₂₆H₁₈F₄N₆O₂

Base Information

Chemical Name:C₂₆H₁₈F₄N₆O₂
CAS No.:1422175-65-2
Molecular Formula:C₂₆H₁₈F₄N₆O₂
Molecular Weight:522.462
Hs Code.:

C<sub>26</sub>H<sub>18</sub>F<sub>4</sub>N<sub>6</sub>O<sub>2</sub>

Synonyms:C₂₆H₁₈F₄N₆O₂

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of C₂₆H₁₈F₄N₆O₂

Chemical Property:

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Technology Process of C₂₆H₁₈F₄N₆O₂

There total 9 articles about C₂₆H₁₈F₄N₆O₂ which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 1422175-62-9
(5-{[5-(4-fluorophenyl)-2-trifluoromethyl-3H-imidazole-4-carbonyl]amino}-2-methylphenyl)amine

: 26663-77-4
methyl 1H-benzo[d]imidazole-5-carboxylate

: 1422175-65-2
C₂₆H₁₈F₄N₆O₂

Guidance literature:: With tetramethyl aluminum; In toluene; at 160 ℃; for 0.333333h; Microwave irradiation;

Reference yield:

: 7292-73-1
(2RS)-N-(p-fluorophenyl)glycine

: 1422175-65-2
C₂₆H₁₈F₄N₆O₂

Guidance literature:: Multi-step reaction with 6 steps

1.1: 2 h / 20 °C

2.1: tributylphosphine / toluene / 12 h / 20 °C

3.1: 5%-palladium/activated carbon; hydrogen / ethanol / 2585.81 Torr

4.1: HATU; N-ethyl-N,N-diisopropylamine / dichloromethane / 0.25 h

4.2: 48 h / Reflux

5.1: trifluoroacetic acid / dichloromethane

6.1: tetramethyl aluminum / toluene / 0.33 h / 160 °C / Microwave irradiation

With tributylphosphine; 5%-palladium/activated carbon; hydrogen; N-ethyl-N,N-diisopropylamine; HATU; trifluoroacetic acid; In ethanol; dichloromethane; toluene;

Reference yield:

: C₁₀H₅F₄NO₂

: 1422175-65-2
C₂₆H₁₈F₄N₆O₂

Guidance literature:: Multi-step reaction with 5 steps

1.1: tributylphosphine / toluene / 12 h / 20 °C

2.1: 5%-palladium/activated carbon; hydrogen / ethanol / 2585.81 Torr

3.1: HATU; N-ethyl-N,N-diisopropylamine / dichloromethane / 0.25 h

3.2: 48 h / Reflux

4.1: trifluoroacetic acid / dichloromethane

5.1: tetramethyl aluminum / toluene / 0.33 h / 160 °C / Microwave irradiation

With tributylphosphine; 5%-palladium/activated carbon; hydrogen; N-ethyl-N,N-diisopropylamine; HATU; trifluoroacetic acid; In ethanol; dichloromethane; toluene;