CYCLOHEXYL(PIPERAZINO)METHANONE HYDROCHLORIDE

Base Information

• Chemical Name: CYCLOHEXYL(PIPERAZINO)METHANONE HYDROCHLORIDE
• CAS No.: 81486-91-1
• Molecular Formula: C₁₁H₂₀N₂O*ClH
• Molecular Weight: 232.754
• Hs Code.: 2933599590
• Mol file: 81486-91-1.mol

Synonyms:Piperazine,1-(cyclohexylcarbonyl)-, monohydrochloride (9CI)

Chemical Property of CYCLOHEXYL(PIPERAZINO)METHANONE HYDROCHLORIDE

Chemical Property:

• Vapor Pressure: 3.75E-06mmHg at 25°C
• Melting Point: 255-258
• Boiling Point: 380.2°C at 760 mmHg
• Flash Point: 183.7°C
• PSA: 32.34000
• LogP: 2.06720

Purity/Quality:

99.90% ^*data from raw suppliers

1-(Cyclohexylcarbonyl)piperazineHCl 97% ^*data from reagent suppliers

Safty Information:

• Hazard Codes: Xi
• Statements: 36/37/38
• Safety Statements: 26-36/37/39

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of CYCLOHEXYL(PIPERAZINO)METHANONE HYDROCHLORIDE

There total 2 articles about CYCLOHEXYL(PIPERAZINO)METHANONE HYDROCHLORIDE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 71.0%

cyclohexanylcarbonyl chloride (2719-27-9) + 1-t-Butoxycarbonylpiperazine (57260-71-6) → cyclohexyl(piperazin-1-yl)methanone hydrochloride (81486-91-1)

Guidance literature:

cyclohexanylcarbonyl chloride; 1-t-Butoxycarbonylpiperazine; With triethylamine; In dichloromethane; for 1h; Inert atmosphere;

With hydrogenchloride; In diethyl ether; dichloromethane; at 20 ℃; for 24h;

DOI:10.1039/c2ra21902f

Reference yield:

→ cyclohexyl(piperazin-1-yl)methanone hydrochloride (81486-91-1)

Guidance literature:

upstream raw materials:

cyclohexanylcarbonyl chloride

1-t-Butoxycarbonylpiperazine