(R)-methyl 2-(7-(3-(3,4-difluorophenyl)ureido)dibenzo[b,d]furan-3-sulfonamido)-3-methylbutanoate

Base Information

Chemical Name:(R)-methyl 2-(7-(3-(3,4-difluorophenyl)ureido)dibenzo[b,d]furan-3-sulfonamido)-3-methylbutanoate
CAS No.:1025720-20-0
Molecular Formula:C₂₅H₂₃F₂N₃O₆S
Molecular Weight:531.537
Hs Code.:

Synonyms:(R)-methyl 2-(7-(3-(3,4-difluorophenyl)ureido)dibenzo[b,d]furan-3-sulfonamido)-3-methylbutanoate

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Chemical Property of (R)-methyl 2-(7-(3-(3,4-difluorophenyl)ureido)dibenzo[b,d]furan-3-sulfonamido)-3-methylbutanoate

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Technology Process of (R)-methyl 2-(7-(3-(3,4-difluorophenyl)ureido)dibenzo[b,d]furan-3-sulfonamido)-3-methylbutanoate

There total 1 articles about (R)-methyl 2-(7-(3-(3,4-difluorophenyl)ureido)dibenzo[b,d]furan-3-sulfonamido)-3-methylbutanoate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 72.0%

: 1025720-18-6
(R)-methyl 3-methyl-2-(7-aminodibenzo[b,d]furan-3-sulfonamido)butanoate

: 42601-04-7
3,4-difluorophenyl isocyanate

: 1025720-20-0
(R)-methyl 2-(7-(3-(3,4-difluorophenyl)ureido)dibenzo[b,d]furan-3-sulfonamido)-3-methylbutanoate

Guidance literature:: In tetrahydrofuran; at 120 ℃; for 0.333333h; Microwave irradiation;

Reference yield: 95.0%

: 1025720-20-0
(R)-methyl 2-(7-(3-(3,4-difluorophenyl)ureido)dibenzo[b,d]furan-3-sulfonamido)-3-methylbutanoate

: 1025718-26-6
(R)-2-(7-(3-(3,4-difluorophenyl)ureido)dibenzo[b,d]furan-3-sulfonamido)-3-methylbutanoic acid

Guidance literature:: (R)-methyl 2-(7-(3-(3,4-difluorophenyl)ureido)dibenzo[b,d]furan-3-sulfonamido)-3-methylbutanoate; With methanol; lithium hydroxide; water; In tetrahydrofuran; at 20 ℃; for 96h;

pH=~ 1; Acidic aqueous solution;