2-oxo-4-phenylcyclohexanecarboxylic acid 1-furan-3-ylprop-2-ynyl ester

Base Information

• Chemical Name: 2-oxo-4-phenylcyclohexanecarboxylic acid 1-furan-3-ylprop-2-ynyl ester
• CAS No.: 1374430-65-5
• Molecular Formula: C₂₀H₁₈O₄
• Molecular Weight: 322.361
• Mol file: 1374430-65-5.mol

Synonyms:2-oxo-4-phenylcyclohexanecarboxylic acid 1-furan-3-ylprop-2-ynyl ester

Chemical Property of 2-oxo-4-phenylcyclohexanecarboxylic acid 1-furan-3-ylprop-2-ynyl ester

Chemical Property:

Purity/Quality:

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Technology Process of 2-oxo-4-phenylcyclohexanecarboxylic acid 1-furan-3-ylprop-2-ynyl ester

There total 1 articles about 2-oxo-4-phenylcyclohexanecarboxylic acid 1-furan-3-ylprop-2-ynyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 44.0%

1-(furan-3-yl)-1-hydroxy-2-propyne (169377-39-3) + methyl 2-oxo-4-phenylcyclohexanecarboxylate (1141891-66-8) → 2-oxo-4-phenylcyclohexanecarboxylic acid 1-furan-3-ylprop-2-ynyl ester (1374430-65-5)

Guidance literature:

In toluene; at 20 ℃; for 122h; Reflux; Inert atmosphere;

DOI:10.1002/chem.201103246

Reference yield: 76.0%

2-oxo-4-phenylcyclohexanecarboxylic acid 1-furan-3-ylprop-2-ynyl ester (1374430-65-5) → 2-furan-3-yl-3-methyl-6-phenyl-4,5,6,7-tetrahydrobenzofuran (1374431-14-7)

Guidance literature:

With tris(dibenzylideneacetone)dipalladium⁽⁰⁾ chloroform complex; 1,1'-bis-(diphenylphosphino)ferrocene; In 1,4-dioxane; at 20 - 65 ℃; for 1h; Inert atmosphere;

DOI:10.1002/chem.201103246

upstream raw materials:

1-(furan-3-yl)-1-hydroxy-2-propyne

methyl 2-oxo-4-phenylcyclohexanecarboxylate

Downstream raw materials:

2-furan-3-yl-3-methyl-6-phenyl-4,5,6,7-tetrahydrobenzofuran