2-Chloro-3,4-dimethoxybenzoic acid

Base Information

Chemical Name:2-Chloro-3,4-dimethoxybenzoic acid
CAS No.:52009-53-7
Molecular Formula:C9H9 Cl O4
Molecular Weight:216.621
Hs Code.:2918990090
European Community (EC) Number:626-227-0
DSSTox Substance ID:DTXSID00379309
Wikidata:Q82169054
Mol file:52009-53-7.mol

Synonyms:2-Chloro-3,4-dimethoxybenzoic acid;52009-53-7;2-Chloro-3,4,-dimethoxybenzoic acid;2-chloro-3,4-dimethoxy-benzoic acid;MFCD00084944;Maybridge1_001936;SCHEMBL2817995;HMS546P22;DTXSID00379309;YSEIYOHXERRMNN-UHFFFAOYSA-N;AMY31024;CCG-56505;AKOS009157530;SY028096;TS-03091;2-Chloro-3,4-dimethoxybenzoic acid, 97%;CS-0099392;FT-0611709;EN300-1968191;A828882;J-200138;SR-01000645456-1

Suppliers and Price of 2-Chloro-3,4-dimethoxybenzoic acid

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
2-Chloro-3,4-dimethoxybenzoic acid
2.5g
$ 250.00

TRC
2-Chloro-3,4-dimethoxybenzoic acid
1g
$ 120.00

SynQuest Laboratories
2-Chloro-3,4-dimethoxybenzoic acid 97%
1 g
$ 28.00

SynQuest Laboratories
2-Chloro-3,4-dimethoxybenzoic acid 97%
5 g
$ 84.00

SynQuest Laboratories
2-Chloro-3,4-dimethoxybenzoic acid 97%
25 g
$ 332.00

Sigma-Aldrich
2-Chloro-3,4-dimethoxybenzoic acid 97%
5g
$ 220.00

Crysdot
2-Chloro-3,4-dimethoxybenzoic acid 97%
25g
$ 208.00

Chemenu
2-Chloro-3,4-dimethoxybenzoic acid 95+%
25g
$ 409.00

Atlantic Research Chemicals
2-Chloro-3,4-dimethoxybenzoic acid 95%
1gm:
$ 45.95

Apolloscientific
2-Chloro-3,4-dimethoxybenzoic acid
25g
$ 301.00

Total 39 raw suppliers

Chemical Property of 2-Chloro-3,4-dimethoxybenzoic acid

Chemical Property:

Vapor Pressure:0.000102mmHg at 25°C
Melting Point:200-204 °C(lit.)
Boiling Point:324.2°C at 760 mmHg
PKA:3.17±0.28(Predicted)
Flash Point:149.9°C
PSA：55.76000
Density:1.337g/cm³
LogP:2.05540
Storage Temp.:Sealed in dry,Room Temperature
XLogP3:2
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:3
Exact Mass:216.0189365
Heavy Atom Count:14
Complexity:209

Purity/Quality:

99%, ^*data from raw suppliers

2-Chloro-3,4-dimethoxybenzoic acid ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:
Safety Statements: 22-24/25

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:COC1=C(C(=C(C=C1)C(=O)O)Cl)OC
Uses 2-Chloro-3,4-dimethoxybenzoic acid can be used as a starting material in the four-step synthesis of 14C-labelled N-(2-chloro-3,4-dimethoxybenzylideneamino)guanidinium acetate.

Technology Process of 2-Chloro-3,4-dimethoxybenzoic acid

There total 4 articles about 2-Chloro-3,4-dimethoxybenzoic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 96.0%

: 5417-17-4
2-chloro-3,4-dimethoxybenzaldehyde

: 52009-53-7
2-chloro-3,4-dimethoxy-benzoic acid

Guidance literature:: With sodium chlorite; aminosulfonic acid; In 1,4-dioxane; water; at 0 ℃; for 0.5h; Inert atmosphere;
DOI:10.1016/j.ejmech.2018.06.014

Reference yield: 68.0%

: 925-90-6
ethylmagnesium bromide

: 2-chloro-N,3,4-trimethoxy-N-methylbenzamide

: 52009-53-7
2-chloro-3,4-dimethoxy-benzoic acid

Guidance literature:: In tetrahydrofuran; diethyl ether; at 0 - 20 ℃; for 1.5h; Inert atmosphere;

Reference yield: 40.0%

: 93-07-2
Veratric acid

: 52009-53-7
2-chloro-3,4-dimethoxy-benzoic acid

Guidance literature:: Veratric acid; With n-butyllithium; 2,2,6,6-tetramethylpiperidinyl-lithium; In tetrahydrofuran; hexane; at -78 - 0 ℃;

With hexachloroethane; In tetrahydrofuran; hexane; for 1h; Further stages.; Heating;
DOI:10.1016/j.tet.2008.08.086