1-pentyloxy-3-toluene

Base Information

• Chemical Name: 1-pentyloxy-3-toluene
• CAS No.: 33426-67-4
• Molecular Formula: C₁₂H₁₈O
• Molecular Weight: 178.274
• Mol file: 33426-67-4.mol

Synonyms:1-pentyloxy-3-toluene

Chemical Property of 1-pentyloxy-3-toluene

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
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MSDS Files:

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Technology Process of 1-pentyloxy-3-toluene

There total 9 articles about 1-pentyloxy-3-toluene which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 96.0%

pentan-1-ol (71-41-0) + meta-bromotoluene (591-17-3) → 1-pentyloxy-3-toluene (33426-67-4)

Guidance literature:

pentan-1-ol; With lithium tert-butoxide; at 20 ℃; for 0.0833333h;

meta-bromotoluene; With copper(l) iodide; at 20 - 110 ℃; Sealed tube;

DOI:10.1055/s-0030-1260761

Reference yield: 52.0%

bis(3-methylphenyl)iodonium tetrafluoroborate + pentan-1-ol (71-41-0) → 1-pentyloxy-3-toluene (33426-67-4)

Guidance literature:

pentan-1-ol; With sodium t-butanolate; In toluene; at 0 - 20 ℃; for 0.25h; Inert atmosphere; Schlenk technique;

bis(3-methylphenyl)iodonium tetrafluoroborate; With piperidine; In toluene; at 0 - 40 ℃; for 1h; Inert atmosphere; Schlenk technique;

DOI:10.1002/chem.201703057

Reference yield:

pentan-1-ol (71-41-0) + bis(4-methylphenyl)(trifluoromethanesulfonato)-λ3-iodane → 1-pentyloxy-3-toluene (33426-67-4) + 1-(4-Methylphenoxy)pentane (33426-70-9)

Guidance literature:

pentan-1-ol; With sodium t-butanolate; In toluene; at 0 - 20 ℃; for 0.25h; Inert atmosphere; Schlenk technique;

bis(4-methylphenyl)(trifluoromethanesulfonato)-λ³-iodane; In toluene; at 0 - 20 ℃; for 3h; Overall yield = 51 %; regioselective reaction; Inert atmosphere; Schlenk technique;

DOI:10.1002/chem.201703057

upstream raw materials:

(+/-)-1-m-Tolyloxy-pentanol-⁽³⁾

3-m-Tolyloxy-propionaldehyd-semicarbazon

3-<3-Methyl-phenoxy>-propanal

pentan-1-ol