1-(4-chlorophenyl)-5-methyl-1H-pyrazole-4-carbonyl chloride

Base Information

Chemical Name:1-(4-chlorophenyl)-5-methyl-1H-pyrazole-4-carbonyl chloride
CAS No.:288252-38-0
Molecular Formula:C11H8 Cl2 N2 O
Molecular Weight:255.103
Hs Code.:2933199090
DSSTox Substance ID:DTXSID20379826
Wikidata:Q82169819
Mol file:288252-38-0.mol

Synonyms:288252-38-0;1-(4-chlorophenyl)-5-methyl-1H-pyrazole-4-carbonyl chloride;1-(4-chlorophenyl)-5-methylpyrazole-4-carbonyl chloride;1H-Pyrazole-4-carbonyl chloride, 1-(4-chlorophenyl)-5-methyl-;SCHEMBL1420171;DTXSID20379826;KUQHQFYKJPXTNB-UHFFFAOYSA-N;MFCD03407325;MS-22158;FT-0605693;J-503285;1-(4-Chlorophenyl)-5-methylpyrazole-4-carboxylic chloride;1-(4-chloro-phenyl)-5-methyl-1H-pyrazole-4-carbonyl chloride

Suppliers and Price of 1-(4-chlorophenyl)-5-methyl-1H-pyrazole-4-carbonyl chloride

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

American Custom Chemicals Corporation
1-(4-CHLOROPHENYL)-5-METHYL-1H-PYRAZOLE-4-CARBONYL CHLORIDE 95.00%
5G
$ 1283.09

American Custom Chemicals Corporation
1-(4-CHLOROPHENYL)-5-METHYL-1H-PYRAZOLE-4-CARBONYL CHLORIDE 95.00%
1G
$ 793.14

American Custom Chemicals Corporation
1-(4-CHLOROPHENYL)-5-METHYL-1H-PYRAZOLE-4-CARBONYL CHLORIDE 95.00%
250MG
$ 631.85

Total 3 raw suppliers

Chemical Property of 1-(4-chlorophenyl)-5-methyl-1H-pyrazole-4-carbonyl chloride

Chemical Property:

Vapor Pressure:2.5E-05mmHg at 25°C
Melting Point:115 °C
Boiling Point:358.7°C at 760 mmHg
Flash Point:170.7°C
PSA：34.89000
Density:1.39g/cm³
LogP:3.21310
XLogP3:3.4
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:2
Exact Mass:254.0013683
Heavy Atom Count:16
Complexity:267

Purity/Quality:

98%min ^*data from raw suppliers

1-(4-CHLOROPHENYL)-5-METHYL-1H-PYRAZOLE-4-CARBONYL CHLORIDE 95.00% ^*data from reagent suppliers

Safty Information:

Pictogram(s): R34:Causes burns.;
Hazard Codes: C:Corrosive;
Statements: R34:Causes burns.;
Safety Statements: S26:In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.; S36/37/39:Wear suitabl

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC1=C(C=NN1C2=CC=C(C=C2)Cl)C(=O)Cl

Technology Process of 1-(4-chlorophenyl)-5-methyl-1H-pyrazole-4-carbonyl chloride

There total 3 articles about 1-(4-chlorophenyl)-5-methyl-1H-pyrazole-4-carbonyl chloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

: 187998-35-2
1-(4-chlorophenyl)-5-methyl-1H-pyrazole-4-carboxylic acid

: 288252-38-0
1-(4-chloro-phenyl)-5-methyl-1H-pyrazole-4-carbonyl chloride

Guidance literature:: With thionyl chloride; for 1h; Reflux;

Reference yield:

: 169548-94-1
1-(4-chlorophenyl)-5-methyl-1H-pyrazole-4-carboxylic acid ethyl ester

: 288252-38-0
1-(4-chloro-phenyl)-5-methyl-1H-pyrazole-4-carbonyl chloride

Guidance literature:: Multi-step reaction with 2 steps

1.1: potassium hydroxide; water / tetrahydrofuran; methanol / 10 h / 25 °C

1.2: pH 2 / Acidic aqueous solution

2.1: oxalyl dichloride / N,N-dimethyl-formamide / dichloromethane / 3 h / 25 °C

With potassium hydroxide; oxalyl dichloride; water; N,N-dimethyl-formamide; In tetrahydrofuran; methanol; dichloromethane;

Reference yield:

: 134653-70-6,51145-57-4
ethyl 2-[(dimethylamino)methylene]-3-oxobutanoate

: 288252-38-0
1-(4-chloro-phenyl)-5-methyl-1H-pyrazole-4-carbonyl chloride

Guidance literature:: Multi-step reaction with 3 steps

1.1: triethylamine / acetonitrile / 10 h / 25 °C

2.1: potassium hydroxide; water / tetrahydrofuran; methanol / 10 h / 25 °C

2.2: pH 2 / Acidic aqueous solution

3.1: oxalyl dichloride / N,N-dimethyl-formamide / dichloromethane / 3 h / 25 °C

With potassium hydroxide; oxalyl dichloride; water; triethylamine; N,N-dimethyl-formamide; In tetrahydrofuran; methanol; dichloromethane; acetonitrile;