3-O-acetyl-5-O-benzoyl-1,2-O-isopropylidene-α-D-ribofuranose

Base Information

• Chemical Name: 3-O-acetyl-5-O-benzoyl-1,2-O-isopropylidene-α-D-ribofuranose
• CAS No.: 115236-89-0
• Molecular Formula: C₁₇H₂₀O₇
• Molecular Weight: 336.342
• Mol file: 115236-89-0.mol

Synonyms:3-O-acetyl-5-O-benzoyl-1,2-O-isopropylidene-α-D-ribofuranose

Chemical Property of 3-O-acetyl-5-O-benzoyl-1,2-O-isopropylidene-α-D-ribofuranose

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 3-O-acetyl-5-O-benzoyl-1,2-O-isopropylidene-α-D-ribofuranose

There total 5 articles about 3-O-acetyl-5-O-benzoyl-1,2-O-isopropylidene-α-D-ribofuranose which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

acetic anhydride (108-24-7) + 5-O-benzoyl-α-D-xylofuranose (6022-96-4) → O3-acetyl-O5-benzoyl-O1,O2-isopropylidene-α-D-xylofuranose (115236-89-0)

Guidance literature:

With pyridine; for 24h; Ambient temperature;

Reference yield: 87.5%

((3aR,5R,65,6aR)-6-hydroxy-2,2-dimethyltetrahydrofuro[2,3-d][1,3]dioxol-5-yl)methyl benzoate (6612-91-5) + acetic anhydride (108-24-7) → 3-O-acetyl-5-O-benzoyl-1,2-O-isopropylidene-α-D-ribofuranose (115236-89-0)

Guidance literature:

In pyridine; at 20 ℃; for 16h;

DOI:10.1016/0008-6215(88)84024-2

Reference yield:

1,2-O-isopropylidene-α-D-xylose (20031-21-4) → O3-acetyl-O5-benzoyl-O1,O2-isopropylidene-α-D-xylofuranose (115236-89-0)

Guidance literature:

Multi-step reaction with 2 steps

1: 93 percent / pyridine / CH₂Cl₂ / 24 h / Ambient temperature

2: 100 percent / pyridine / 24 h / Ambient temperature

With pyridine; In dichloromethane;

upstream raw materials:

acetic anhydride

5-O-benzoyl-α-D-xylofuranose

benzoyl chloride

1,2-O-isopropylidene-α-D-xylose

Downstream raw materials:

1-(2',3'-di-O-acetyl-5'-O-benzoyl-β-D-xylofuranosyl)thymine

Benzoic acid (2R,3R,4S,5S)-3,4,5-triacetoxy-tetrahydro-furan-2-ylmethyl ester

Benzoic acid (2R,3R,4S,5R)-3,4,5-triacetoxy-tetrahydro-furan-2-ylmethyl ester

1,2,3-tri-O-acetyl-5-O-benzoyl-β-D-ribofuranose