(+)-(2S,4S,6S)-2-[3-[(4S,6S)-6-[(2R)-2-acetoxy-4-[(triisopropylsilyl)oxy]butyl]-2,2-dimethyl-1,3-dioxan-4-yl]-2-oxopropyl]tetrahydro-6-[(triisopropylsilyl)oxy]-2H-pyran-4-yl 4-methoxybenzoate

Base Information

Chemical Name:(+)-(2S,4S,6S)-2-[3-[(4S,6S)-6-[(2R)-2-acetoxy-4-[(triisopropylsilyl)oxy]butyl]-2,2-dimethyl-1,3-dioxan-4-yl]-2-oxopropyl]tetrahydro-6-[(triisopropylsilyl)oxy]-2H-pyran-4-yl 4-methoxybenzoate
CAS No.:383191-64-8
Molecular Formula:C₄₆H₈₀O₁₁Si₂
Molecular Weight:865.306
Hs Code.:

(+)-(2S,4S,6S)-2-[3-[(4S,6S)-6-[(2R)-2-acetoxy-4-[(triisopropylsilyl)oxy]butyl]-2,2-dimethyl-1,3-dioxan-4-yl]-2-oxopropyl]tetrahydro-6-[(triisopropylsilyl)oxy]-2H-pyran-4-yl 4-methoxybenzoate

Synonyms:(+)-(2S,4S,6S)-2-[3-[(4S,6S)-6-[(2R)-2-acetoxy-4-[(triisopropylsilyl)oxy]butyl]-2,2-dimethyl-1,3-dioxan-4-yl]-2-oxopropyl]tetrahydro-6-[(triisopropylsilyl)oxy]-2H-pyran-4-yl 4-methoxybenzoate

Suppliers and Price of (+)-(2S,4S,6S)-2-[3-[(4S,6S)-6-[(2R)-2-acetoxy-4-[(triisopropylsilyl)oxy]butyl]-2,2-dimethyl-1,3-dioxan-4-yl]-2-oxopropyl]tetrahydro-6-[(triisopropylsilyl)oxy]-2H-pyran-4-yl 4-methoxybenzoate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of (+)-(2S,4S,6S)-2-[3-[(4S,6S)-6-[(2R)-2-acetoxy-4-[(triisopropylsilyl)oxy]butyl]-2,2-dimethyl-1,3-dioxan-4-yl]-2-oxopropyl]tetrahydro-6-[(triisopropylsilyl)oxy]-2H-pyran-4-yl 4-methoxybenzoate

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of (+)-(2S,4S,6S)-2-[3-[(4S,6S)-6-[(2R)-2-acetoxy-4-[(triisopropylsilyl)oxy]butyl]-2,2-dimethyl-1,3-dioxan-4-yl]-2-oxopropyl]tetrahydro-6-[(triisopropylsilyl)oxy]-2H-pyran-4-yl 4-methoxybenzoate

There total 4 articles about (+)-(2S,4S,6S)-2-[3-[(4S,6S)-6-[(2R)-2-acetoxy-4-[(triisopropylsilyl)oxy]butyl]-2,2-dimethyl-1,3-dioxan-4-yl]-2-oxopropyl]tetrahydro-6-[(triisopropylsilyl)oxy]-2H-pyran-4-yl 4-methoxybenzoate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 4-Methoxy-benzoic acid (2S,4S,6S)-2-{3-[(4S,6S)-6-((S)-2-methanesulfonyloxy-4-triisopropylsilanyloxy-butyl)-2,2-dimethyl-[1,3]dioxan-4-yl]-2-oxo-propyl}-6-triisopropylsilanyloxy-tetrahydro-pyran-4-yl ester

: 3396-11-0
cesium acetate

: 383191-64-8
(+)-(2S,4S,6S)-2-[3-[(4S,6S)-6-[(2R)-2-acetoxy-4-[(triisopropylsilyl)oxy]butyl]-2,2-dimethyl-1,3-dioxan-4-yl]-2-oxopropyl]tetrahydro-6-[(triisopropylsilyl)oxy]-2H-pyran-4-yl 4-methoxybenzoate

: 4-Methoxy-benzoic acid (2S,4S,6S)-2-{3-[(4S,6S)-6-((S)-2-acetoxy-4-triisopropylsilanyloxy-butyl)-2,2-dimethyl-[1,3]dioxan-4-yl]-2-oxo-propyl}-6-triisopropylsilanyloxy-tetrahydro-pyran-4-yl ester

Guidance literature:: With 18-crown-6 ether; In benzene; at 80 ℃; for 6h;
DOI:10.1021/jo010172u

Reference yield:

: 383191-63-7
(+)-(2S,4S)-2-[3-[(4S,6S)-6-[(2S)-2-hydroxy-4-[(triisopropylsilyl)oxy]butyl]-2,2-dimethyl-1,3-dioxan-4-yl]-2-oxopropyl]tetrahydro-6-[(triisopropylsilyl)oxy]-2H-pyran-4-yl 4-methoxybenzoate

: 383191-64-8
(+)-(2S,4S,6S)-2-[3-[(4S,6S)-6-[(2R)-2-acetoxy-4-[(triisopropylsilyl)oxy]butyl]-2,2-dimethyl-1,3-dioxan-4-yl]-2-oxopropyl]tetrahydro-6-[(triisopropylsilyl)oxy]-2H-pyran-4-yl 4-methoxybenzoate

Guidance literature:: Multi-step reaction with 2 steps

1: pyridine; DMAP / CH₂Cl₂ / 4 h / 20 °C

2: 94 mg / 18-crown-6 ether / benzene / 6 h / 80 °C

With pyridine; dmap; 18-crown-6 ether; In dichloromethane; benzene;
DOI:10.1021/jo010172u

Reference yield:

: (+)-(2S,4S)-2-[3-[(4S,6R)-6-[(2S)-2,4-dihydroxybutyl]-2,2-dimethyl-1,3-dioxan-4-yl]-2-oxopropyl]tetrahydro-6-hydroxy-2H-pyran-4-yl 4-methoxybenzoate

: 383191-64-8
(+)-(2S,4S,6S)-2-[3-[(4S,6S)-6-[(2R)-2-acetoxy-4-[(triisopropylsilyl)oxy]butyl]-2,2-dimethyl-1,3-dioxan-4-yl]-2-oxopropyl]tetrahydro-6-[(triisopropylsilyl)oxy]-2H-pyran-4-yl 4-methoxybenzoate

Guidance literature:: Multi-step reaction with 3 steps

1: 73 percent / imidazole / dimethylformamide / 48 h / 20 °C

2: pyridine; DMAP / CH₂Cl₂ / 4 h / 20 °C

3: 94 mg / 18-crown-6 ether / benzene / 6 h / 80 °C

With pyridine; 1H-imidazole; dmap; 18-crown-6 ether; In dichloromethane; N,N-dimethyl-formamide; benzene;
DOI:10.1021/jo010172u