tert-butyl 4-({5-[({5-[(2,4,5-trifluorophenyl)amino]-1,3,4-oxadiazol-2-yl}-carbonyl)amino]pyridin-2-yl}oxy)cyclohexanecarboxylate

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Chemical Name:tert-butyl 4-({5-[({5-[(2,4,5-trifluorophenyl)amino]-1,3,4-oxadiazol-2-yl}-carbonyl)amino]pyridin-2-yl}oxy)cyclohexanecarboxylate
CAS No.:1124173-82-5
Molecular Formula:C₂₅H₂₆F₃N₅O₅
Molecular Weight:533.507
Hs Code.:

Synonyms:tert-butyl 4-({5-[({5-[(2,4,5-trifluorophenyl)amino]-1,3,4-oxadiazol-2-yl}-carbonyl)amino]pyridin-2-yl}oxy)cyclohexanecarboxylate

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Chemical Property of tert-butyl 4-({5-[({5-[(2,4,5-trifluorophenyl)amino]-1,3,4-oxadiazol-2-yl}-carbonyl)amino]pyridin-2-yl}oxy)cyclohexanecarboxylate

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Technology Process of tert-butyl 4-({5-[({5-[(2,4,5-trifluorophenyl)amino]-1,3,4-oxadiazol-2-yl}-carbonyl)amino]pyridin-2-yl}oxy)cyclohexanecarboxylate

There total 1 articles about tert-butyl 4-({5-[({5-[(2,4,5-trifluorophenyl)amino]-1,3,4-oxadiazol-2-yl}-carbonyl)amino]pyridin-2-yl}oxy)cyclohexanecarboxylate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

: 362690-53-7
2,4,5-trifluorophenyl isothiocyanate

: 1124173-84-7
tert-butyl 4-[(5-{[hydrazino(oxo)acetyl]amino}pyridin-2-yl)oxy]cyclohexanecarboxylate

: 1124173-82-5
tert-butyl 4-({5-[({5-[(2,4,5-trifluorophenyl)amino]-1,3,4-oxadiazol-2-yl}-carbonyl)amino]pyridin-2-yl}oxy)cyclohexanecarboxylate

Guidance literature:: 2,4,5-trifluorophenyl isothiocyanate; tert-butyl 4-[(5-{[hydrazino(oxo)acetyl]amino}pyridin-2-yl)oxy]cyclohexanecarboxylate; In N,N-dimethyl-formamide; at 20 ℃; for 3h;

With 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; In N,N-dimethyl-formamide; at 20 ℃; for 16h;

Reference yield: 68.0%

: 1124173-82-5
tert-butyl 4-({5-[({5-[(2,4,5-trifluorophenyl)amino]-1,3,4-oxadiazol-2-yl}-carbonyl)amino]pyridin-2-yl}oxy)cyclohexanecarboxylate

: 1124172-83-3
4-(5-(5-(2,4,5-trifluorophenylamino)-1,3,4-oxadiazole-2-carboxamido)pyridin-2-yloxy)cyclohexanecarboxylic acid

Guidance literature:: tert-butyl 4-({5-[({5-[(2,4,5-trifluorophenyl)amino]-1,3,4-oxadiazol-2-yl}-carbonyl)amino]pyridin-2-yl}oxy)cyclohexanecarboxylate; With trifluoroacetic acid; In tetrahydrofuran; at 20 ℃; for 18h;

With potassium carbonate; In water; pH=7;