1,1-bis(4-fluorophenyl)-2-(1-methyl-1H-tetrazol-5-yl)ethene

Base Information

• Chemical Name: 1,1-bis(4-fluorophenyl)-2-(1-methyl-1H-tetrazol-5-yl)ethene
• CAS No.: 118875-66-4
• Molecular Formula: C₁₆H₁₂F₂N₄
• Molecular Weight: 298.295
• Mol file: 118875-66-4.mol

Synonyms:1,1-bis(4-fluorophenyl)-2-(1-methyl-1H-tetrazol-5-yl)ethene

Chemical Property of 1,1-bis(4-fluorophenyl)-2-(1-methyl-1H-tetrazol-5-yl)ethene

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 1,1-bis(4-fluorophenyl)-2-(1-methyl-1H-tetrazol-5-yl)ethene

There total 3 articles about 1,1-bis(4-fluorophenyl)-2-(1-methyl-1H-tetrazol-5-yl)ethene which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

1,1-bis(4-fluorophenyl)-2-(1-methyl-1H-tetrazol-5-yl)ethanol (118875-65-3) → 1,1-bis(4-fluorophenyl)-2-(1-methyl-1H-tetrazol-5-yl)ethene (118875-66-4)

Guidance literature:

With toluene-4-sulfonic acid; In toluene; Yield given; Heating;

DOI:10.1021/jm00129a004

Reference yield:

4,4'-Difluorobenzophenone (345-92-6) → 1,1-bis(4-fluorophenyl)-2-(1-methyl-1H-tetrazol-5-yl)ethene (118875-66-4)

Guidance literature:

Multi-step reaction with 2 steps

1: 1) n-BuLi / 1) THF, -78 deg C

2: p-TsOH / toluene / Heating

With n-butyllithium; toluene-4-sulfonic acid; In toluene;

DOI:10.1021/jm00129a004

Reference yield:

→ 1,1-bis(4-fluorophenyl)-2-(1-methyl-1H-tetrazol-5-yl)ethene (118875-66-4)

Guidance literature:

upstream raw materials:

1,1-bis(4-fluorophenyl)-2-(1-methyl-1H-tetrazol-5-yl)ethanol

4,4'-Difluorobenzophenone

Downstream raw materials:

ethyl 9,9-bis(4-fluorophenyl)-5-hydroxy-8-(1-methyl-1H-tetrazol-5-yl)-3-oxo-6,8-nonadienoate

ethyl (+/-)-erythro-9,9-bis(4-fluorophenyl)-3,5-dihydroxy-8-(1-methyl-1H-tetrazol-5-yl)-6,8-nonadienoate

5,5-bis(4-fluorophenyl)-4-(1-methyl-1H-tetrazol-5-yl)-2,4-pentadienal

3,3-bis(4-fluorophenyl)-2-(1-methyl-1H-tetrazol-5-yl)-2-propenal