4-Methyl-2-phenylpyrimidine-5-carbohydrazide

Base Information

Chemical Name:4-Methyl-2-phenylpyrimidine-5-carbohydrazide
CAS No.:100517-70-2
Molecular Formula:C12H12 N4 O
Molecular Weight:228.253
Hs Code.:
DSSTox Substance ID:DTXSID30380145
Wikidata:Q82170230
Mol file:100517-70-2.mol

Synonyms:100517-70-2;4-methyl-2-phenylpyrimidine-5-carbohydrazide;4-methyl-2-phenyl-5-pyrimidinecarbohydrazide;5-Pyrimidinecarboxylicacid,4-methyl-2-phenyl-,hydrazide;DTXSID30380145;MFCD03086119;AKOS015912108;FT-0619022;J-515722

Suppliers and Price of 4-Methyl-2-phenylpyrimidine-5-carbohydrazide

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

American Custom Chemicals Corporation
4-METHYL-2-PHENYL-5-PYRIMIDINECARBOHYDRAZIDE 95.00%
1G
$ 737.52

Total 10 raw suppliers

Chemical Property of 4-Methyl-2-phenylpyrimidine-5-carbohydrazide

Chemical Property:

Melting Point:185oC
PSA：80.90000
Density:1.234g/cm3
LogP:2.14670
XLogP3:0.8
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:2
Exact Mass:228.10111102
Heavy Atom Count:17
Complexity:265

Purity/Quality:

99% ^*data from raw suppliers

4-METHYL-2-PHENYL-5-PYRIMIDINECARBOHYDRAZIDE 95.00% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:
Safety Statements: S24/25:Avoid contact with skin and eyes.;

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC1=NC(=NC=C1C(=O)NN)C2=CC=CC=C2

Technology Process of 4-Methyl-2-phenylpyrimidine-5-carbohydrazide

There total 3 articles about 4-Methyl-2-phenylpyrimidine-5-carbohydrazide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 83.0%

: 70733-12-9
ethyl 4-methyl-2-phenyl-5-pyrimidinecarboxylate

: 100517-70-2
4-methyl-2-phenylpyrimidine-5-carbohydrazide

Guidance literature:: With hydrazine hydrate; In ethanol; at 55 ℃; for 4h;
DOI:10.3390/molecules181011683

Reference yield:

: 134653-70-6,51145-57-4
ethyl 2-[(dimethylamino)methylene]-3-oxobutanoate

: 100517-70-2
4-methyl-2-phenylpyrimidine-5-carbohydrazide

Guidance literature:: Multi-step reaction with 2 steps

1: sodium / ethanol / 2 h / 20 °C / Inert atmosphere

2: hydrazine hydrate / ethanol / 4 h / 55 °C

With sodium; hydrazine hydrate; In ethanol;
DOI:10.3390/molecules181011683