(1R,2R,4S)-4-(methanesulfonyl-methyl-amino)-cyclopentane-1,2-dicarboxylic acid 1-{[(1S,2S,4R)-4-((S)-1-benzylcarbamoyl-2-methyl-propylcarbamoyl)-1-(3,5-difluoro-phenoxymethyl)-2-hydroxy-4-methoxy-butyl]-amide} 2-{[(S)-1-(4-chloro-phenyl)-ethyl]-amide}

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Chemical Name:(1R,2R,4S)-4-(methanesulfonyl-methyl-amino)-cyclopentane-1,2-dicarboxylic acid 1-{[(1S,2S,4R)-4-((S)-1-benzylcarbamoyl-2-methyl-propylcarbamoyl)-1-(3,5-difluoro-phenoxymethyl)-2-hydroxy-4-methoxy-butyl]-amide} 2-{[(S)-1-(4-chloro-phenyl)-ethyl]-amide}
CAS No.:1067651-50-6
Molecular Formula:C₄₂H₅₄ClF₂N₅O₉S
Molecular Weight:878.435
Hs Code.:

(1R,2R,4S)-4-(methanesulfonyl-methyl-amino)-cyclopentane-1,2-dicarboxylic acid 1-{[(1S,2S,4R)-4-((S)-1-benzylcarbamoyl-2-methyl-propylcarbamoyl)-1-(3,5-difluoro-phenoxymethyl)-2-hydroxy-4-methoxy-butyl]-amide} 2-{[(S)-1-(4-chloro-phenyl)-ethyl]-amide}

Synonyms:(1R,2R,4S)-4-(methanesulfonyl-methyl-amino)-cyclopentane-1,2-dicarboxylic acid 1-{[(1S,2S,4R)-4-((S)-1-benzylcarbamoyl-2-methyl-propylcarbamoyl)-1-(3,5-difluoro-phenoxymethyl)-2-hydroxy-4-methoxy-butyl]-amide} 2-{[(S)-1-(4-chloro-phenyl)-ethyl]-amide}

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Chemical Property of (1R,2R,4S)-4-(methanesulfonyl-methyl-amino)-cyclopentane-1,2-dicarboxylic acid 1-{[(1S,2S,4R)-4-((S)-1-benzylcarbamoyl-2-methyl-propylcarbamoyl)-1-(3,5-difluoro-phenoxymethyl)-2-hydroxy-4-methoxy-butyl]-amide} 2-{[(S)-1-(4-chloro-phenyl)-ethyl]-amide}

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Technology Process of (1R,2R,4S)-4-(methanesulfonyl-methyl-amino)-cyclopentane-1,2-dicarboxylic acid 1-{[(1S,2S,4R)-4-((S)-1-benzylcarbamoyl-2-methyl-propylcarbamoyl)-1-(3,5-difluoro-phenoxymethyl)-2-hydroxy-4-methoxy-butyl]-amide} 2-{[(S)-1-(4-chloro-phenyl)-ethyl]-amide}

There total 1 articles about (1R,2R,4S)-4-(methanesulfonyl-methyl-amino)-cyclopentane-1,2-dicarboxylic acid 1-{[(1S,2S,4R)-4-((S)-1-benzylcarbamoyl-2-methyl-propylcarbamoyl)-1-(3,5-difluoro-phenoxymethyl)-2-hydroxy-4-methoxy-butyl]-amide} 2-{[(S)-1-(4-chloro-phenyl)-ethyl]-amide} which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 1067652-29-2
(1R,2R,4S)-2-[(S)-1-(4-chloro-phenyl)-ethylcarbamoyl]-4-(methanesulfonyl-methyl-amino)-cyclopentanecarboxylic acid methyl ester

: 1067652-47-4
(2R,4S,5S)-5-amino-6-(3,5-difluoro-phenoxy)-4-hydroxy-2-methoxy-hexanoic acid ((S)-1-benzylcarbamoyl-2-methyl-propyl)-amide

: 1067651-50-6
(1R,2R,4S)-4-(methanesulfonyl-methyl-amino)-cyclopentane-1,2-dicarboxylic acid 1-{[(1S,2S,4R)-4-((S)-1-benzylcarbamoyl-2-methyl-propylcarbamoyl)-1-(3,5-difluoro-phenoxymethyl)-2-hydroxy-4-methoxy-butyl]-amide} 2-{[(S)-1-(4-chloro-phenyl)-ethyl]-amide}

Guidance literature:: (1R,2R,4S)-2-[(S)-1-(4-chloro-phenyl)-ethylcarbamoyl]-4-(methanesulfonyl-methyl-amino)-cyclopentanecarboxylic acid methyl ester; With lithium hydroxide; water; In 1,4-dioxane;

(2R,4S,5S)-5-amino-6-(3,5-difluoro-phenoxy)-4-hydroxy-2-methoxy-hexanoic acid ((S)-1-benzylcarbamoyl-2-methyl-propyl)-amide; With N-ethyl-N,N-diisopropylamine; HATU; In N,N-dimethyl-formamide; for 4h;