FURAN-2-YLMETHYL-P-TOLYL-AMINE

Base Information

• Chemical Name: FURAN-2-YLMETHYL-P-TOLYL-AMINE
• CAS No.: 3139-27-3
• Molecular Formula: C₁₂H₁₃NO
• Molecular Weight: 187.241
• Hs Code.: 2921430090
• Mol file: 3139-27-3.mol

Synonyms:IFLAB-BB F1953-0001;FURAN-2-YLMETHYL-P-TOLYL-AMINE;N1-(2-FURYLMETHYL)-4-METHYLANILINE;N1-(Fur-2-ylmethyl)-4-methylaniline;Furan-2-ylmethyl-p-totyl-amine

Chemical Property of FURAN-2-YLMETHYL-P-TOLYL-AMINE

Chemical Property:

• Vapor Pressure: 0.00181mmHg at 25°C
• Boiling Point: 292.7°Cat760mmHg
• Flash Point: 130.8°C
• PSA: 25.17000
• Density: 1.11g/cm³
• LogP: 3.27310

Purity/Quality:

98%min ^*data from raw suppliers

N-(Furan-2-ylmethyl)-4-methylaniline ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of FURAN-2-YLMETHYL-P-TOLYL-AMINE

There total 14 articles about FURAN-2-YLMETHYL-P-TOLYL-AMINE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 98.0%

furan-2-ylmethanamine (617-89-0) + para-bromotoluene (106-38-7) → N-((furane-2-yl)methyl)-4-methylbenzeneamine (3139-27-3)

Guidance literature:

With copper(I) oxide; N-(2-methylnaphthalen-1-yl)-N'-benzyl oxalamide; potassium hydroxide; In ethanol; at 80 ℃; for 12h; Schlenk technique; Inert atmosphere;

DOI:10.1021/acs.orglett.7b00901

Reference yield: 96.0%

furan-2-ylmethanamine (617-89-0) + para-chlorotoluene (106-43-4) → N-((furane-2-yl)methyl)-4-methylbenzeneamine (3139-27-3)

Guidance literature:

With potassium phosphate; In dimethyl sulfoxide; at 80 ℃; UV-irradiation;

DOI:10.1007/s11426-020-9859-9

Reference yield: 96.0%

N-(furan-2-ylmethylene)-4-methylaniline → N-((furane-2-yl)methyl)-4-methylbenzeneamine (3139-27-3)

Guidance literature:

With sodium tetrahydroborate; In methanol; at 20 ℃;

DOI:10.1016/j.bmc.2007.10.034

upstream raw materials:

furfural

p-toluidine

furfurylidene-p-toluidine

furan-2-ylmethanamine

Downstream raw materials:

N-furfuryl-N-methyl-p-toluidine

Benzotriazol-1-ylmethyl-furan-2-ylmethyl-p-tolyl-amine

Furan-2-ylmethyl-non-2-ynyl-p-tolyl-amine

N-allyl-N-2-furfuryl-p-toluidine

Refernces

• 1、 Chen, Fushan,Deng, Li,Dong, Wenjin,Tang, Jie,Xian, Mo. "Rhodium catalysts with cofactor mimics for the biomimetic reduction of CN bonds". . p. 5564 - 5569. Retrieved 2021/08/25.
• 2、 -. "Oxalic amide ligands, and uses thereof in copper-catalyzed coupling reaction of aryl halides". Page/Page column 72. . Retrieved 2020/01/09.