3-carboxymethylphenyl nonaflate

Base Information

• Chemical Name: 3-carboxymethylphenyl nonaflate
• CAS No.: 873838-38-1
• Molecular Formula: C₁₂H₇F₉O₅S
• Molecular Weight: 434.236
• Mol file: 873838-38-1.mol

Synonyms:3-carboxymethylphenyl nonaflate

Chemical Property of 3-carboxymethylphenyl nonaflate

Chemical Property:

Purity/Quality:

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MSDS Files:

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Technology Process of 3-carboxymethylphenyl nonaflate

There total 1 articles about 3-carboxymethylphenyl nonaflate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 80.0%

Nonafluorobutanesulfonyl fluoride (375-72-4) + methyl 3-hydroxybenzoate (19438-10-9) → 3-carboxymethylphenyl nonaflate (873838-38-1)

Guidance literature:

With dmap; N-ethyl-N,N-diisopropylamine; In dichloromethane; at 0 - 20 ℃;

DOI:10.1021/jo052131u

Reference yield: 94.0%

3-carboxymethylphenyl nonaflate (873838-38-1) + N-methyl-p-toluidine (623-08-5) → 3-(methyl-p-tolyl-amino)-benzoic acid methyl ester

Guidance literature:

With tris(dibenzylideneacetone)dipalladium ⁽⁰⁾; 1-methyl-2,3,4,6,7,8-hexahydro-1H-pyrimido[1,2-a]pyrimidine; 4,5-bis(diphenylphosphino)-9,9-dimethylxanthene; In toluene; at 175 ℃; for 0.5h; microwave irradiation;

DOI:10.1021/jo052131u

Reference yield:

3-carboxymethylphenyl nonaflate (873838-38-1) → Methyl 3-aminobenzoate (4518-10-9)

Guidance literature:

Multi-step reaction with 2 steps

1: 7-methyl-1,5,7-triazabicyclo[4.4.0]dec-5-ene; XantPhos; Pd₂(dba)3 / toluene / 0.33 h / 140 °C / microwave irradiation

2: NH₂OH*HCl; NaOAc / methanol / 0.5 h

With tris(dibenzylideneacetone)dipalladium ⁽⁰⁾; hydroxylamine hydrochloride; sodium acetate; 1-methyl-2,3,4,6,7,8-hexahydro-1H-pyrimido[1,2-a]pyrimidine; 4,5-bis(diphenylphosphino)-9,9-dimethylxanthene; In methanol; toluene;

DOI:10.1021/jo052131u

upstream raw materials:

Nonafluorobutanesulfonyl fluoride

methyl 3-hydroxybenzoate

Downstream raw materials:

Methyl 3-aminobenzoate