1-chloro-3-[(1Z)-2-chloro-3,3,3-trifluoro-1-propenyl]benzene

Base Information

• Chemical Name: 1-chloro-3-[(1Z)-2-chloro-3,3,3-trifluoro-1-propenyl]benzene
• CAS No.: 374590-74-6
• Molecular Formula: C₉H₅Cl₂F₃
• Molecular Weight: 241.04
• Mol file: 374590-74-6.mol

Synonyms:1-chloro-3-[(1Z)-2-chloro-3,3,3-trifluoro-1-propenyl]benzene

Chemical Property of 1-chloro-3-[(1Z)-2-chloro-3,3,3-trifluoro-1-propenyl]benzene

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 1-chloro-3-[(1Z)-2-chloro-3,3,3-trifluoro-1-propenyl]benzene

There total 3 articles about 1-chloro-3-[(1Z)-2-chloro-3,3,3-trifluoro-1-propenyl]benzene which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

1,1,1-Trichloro-2,2,2-trifluoroethane (354-58-5) + 3-chlorobenzaldehyde hydrazone (306773-38-6) → 3-chlorobenzaldehyde N-[-(3-chlorophenyl)methylidene]hydrazone (41097-39-6,6971-97-7) + 1-chloro-3-[(1E)-2-chloro-3,3,3-trifluoro-1-propenyl]benzene + 1-chloro-3-[(1Z)-2-chloro-3,3,3-trifluoro-1-propenyl]benzene (374590-74-6)

Guidance literature:

With copper(I) chloride; ethylenediamine; In ethanol; at 20 ℃; Title compound not separated from byproducts;

DOI:10.1016/S0040-4020(01)00701-3

Reference yield:

m-Chlorobenzaldehyde (587-04-2) → 1-chloro-3-[(1Z)-2-chloro-3,3,3-trifluoro-1-propenyl]benzene (374590-74-6)

Guidance literature:

Multi-step reaction with 2 steps

1: N₂H₄*H₂O / ethanol

2: Cu₂Cl₂; 1,2-ethylenediamine / ethanol / 20 °C

With copper(I) chloride; hydrazine hydrate; ethylenediamine; In ethanol;

DOI:10.1016/S0040-4020(01)00701-3

Reference yield:

1,1,1-Trichloro-2,2,2-trifluoroethane (354-58-5) + m-Chlorobenzaldehyde (587-04-2) → 1-chloro-3-[(1E)-2-chloro-3,3,3-trifluoro-1-propenyl]benzene + 1-chloro-3-[(1Z)-2-chloro-3,3,3-trifluoro-1-propenyl]benzene (374590-74-6)

Guidance literature:

With potassium carbonate; triphenylphosphine; at 100 ℃; for 8h; optical yield given as %de; Neat (no solvent); Inert atmosphere;

DOI:10.1080/00397910802431123

upstream raw materials:

1,1,1-Trichloro-2,2,2-trifluoroethane

3-chlorobenzaldehyde hydrazone

m-Chlorobenzaldehyde