5-Cyano-6-methoxycarbonylmethylsulfanyl-2-methyl-4-phenyl-nicotinic acid ethyl ester

Base Information

Chemical Name:5-Cyano-6-methoxycarbonylmethylsulfanyl-2-methyl-4-phenyl-nicotinic acid ethyl ester
CAS No.:148119-04-4
Molecular Formula:C₁₉H₁₈N₂O₄S
Molecular Weight:370.429
Hs Code.:

Synonyms:5-Cyano-6-methoxycarbonylmethylsulfanyl-2-methyl-4-phenyl-nicotinic acid ethyl ester

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Chemical Property of 5-Cyano-6-methoxycarbonylmethylsulfanyl-2-methyl-4-phenyl-nicotinic acid ethyl ester

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Technology Process of 5-Cyano-6-methoxycarbonylmethylsulfanyl-2-methyl-4-phenyl-nicotinic acid ethyl ester

There total 3 articles about 5-Cyano-6-methoxycarbonylmethylsulfanyl-2-methyl-4-phenyl-nicotinic acid ethyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 80.0%

: 96-34-4
methyl chloroacetate

: 97651-26-8
3-cyano-5-(ethoxycarbonyl)-6-methyl-4-phenylpyridine-2(1H)-thione

: 148119-04-4
5-Cyano-6-methoxycarbonylmethylsulfanyl-2-methyl-4-phenyl-nicotinic acid ethyl ester

Guidance literature:: With potassium carbonate; In acetone; for 3h; Heating;

Reference yield:

: 40219-06-5
benzylidenecyanothioacetamide

: 148119-04-4
5-Cyano-6-methoxycarbonylmethylsulfanyl-2-methyl-4-phenyl-nicotinic acid ethyl ester

Guidance literature:: Multi-step reaction with 2 steps

1: 80 percent / triethylamine / ethanol / 5 h / Heating

2: 80 percent / potassium carbonate / acetone / 3 h / Heating

With potassium carbonate; triethylamine; In ethanol; acetone;

Reference yield:

: 141-97-9
ethyl acetoacetate

: 148119-04-4
5-Cyano-6-methoxycarbonylmethylsulfanyl-2-methyl-4-phenyl-nicotinic acid ethyl ester

Guidance literature:: Multi-step reaction with 2 steps

1: 80 percent / triethylamine / ethanol / 5 h / Heating

2: 80 percent / potassium carbonate / acetone / 3 h / Heating

With potassium carbonate; triethylamine; In ethanol; acetone;