1,3-dibromo-5-n-octylbenzene

Base Information

• Chemical Name: 1,3-dibromo-5-n-octylbenzene
• CAS No.: 75894-99-4
• Molecular Formula: C₁₄H₂₀Br₂
• Molecular Weight: 348.121
• Mol file: 75894-99-4.mol

Synonyms:1,3-dibromo-5-n-octylbenzene

Chemical Property of 1,3-dibromo-5-n-octylbenzene

Chemical Property:

• Refractive Index: 1.5400 to 1.5440

Purity/Quality:

98%,99%, ^*data from raw suppliers

1,3-Dibromo-5-n-octylbenzene >98.0%(GC) ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 1,3-dibromo-5-n-octylbenzene

There total 2 articles about 1,3-dibromo-5-n-octylbenzene which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 48.0%

2,6-dibromo-4-octylaniline (1380609-32-4) → 1,3-dibromo-5-n-octylbenzene (75894-99-4)

Guidance literature:

2,6-dibromo-4-octylaniline; With tert.-butylnitrite; In N,N-dimethyl-formamide; at 50 ℃;

With hydrogenchloride; In diethyl ether; N,N-dimethyl-formamide;

DOI:10.1002/anie.201206096

Reference yield:

C24H51In (1041479-71-3) + (3,5-dibromophenyl)zinc(II) chloride (1205517-08-3) → 3,3',5,5'-tetrabromo-1,1'-biphenyl (16400-50-3) + 1,3-dibromo-5-n-octylbenzene (75894-99-4)

Guidance literature:

With palladium chloride*2MeCN; Desyl chloride; bis[2-(diphenylphosphino)phenyl] ether; In tetrahydrofuran; at 20 ℃; for 5h; chemoselective reaction;

DOI:10.1002/adsc.200800703

Reference yield: 96.0%

1,3-dibromo-5-n-octylbenzene (75894-99-4) → 1-bromo-3-iodo-5-octylbenzene (1427513-93-6)

Guidance literature:

1,3-dibromo-5-n-octylbenzene; With n-butyllithium; In tetrahydrofuran; hexane; at -78 ℃; for 1h;

With 1,2-Diiodoethane; In tetrahydrofuran; hexane; at -78 - 20 ℃; for 2.5h;

DOI:10.1002/anie.201206096

upstream raw materials:

C₂₄H₅₁In

(3,5-dibromophenyl)zinc(II) chloride

2,6-dibromo-4-octylaniline

Downstream raw materials:

1-bromo-3-iodo-5-octylbenzene

Refernces

• 1、 Jin, Liqun,Zhao, Yingsheng,Zhu, Lizheng,Zhang, Heng,Lei, Aiwen. "Highly selective palladium-catalyzed oxidative Csp2-Csp 3 cross-coupling of arylzinc and alkylindium reagents through double transmetallation". supporting information; experimental part. p. 630 - 634. Retrieved 2009/11/30.