2-benzyloxycarbonyl-2,3,4,4a,5,6,7,7a-octahydro-5-methyl-4a-phenyl-cis-1H-cyclopentapyridine

Base Information

Chemical Name:2-benzyloxycarbonyl-2,3,4,4a,5,6,7,7a-octahydro-5-methyl-4a-phenyl-cis-1H-cyclopentapyridine
CAS No.:120402-21-3
Molecular Formula:C₂₃H₂₇NO₂
Molecular Weight:349.473
Hs Code.:

2-benzyloxycarbonyl-2,3,4,4a,5,6,7,7a-octahydro-5-methyl-4a-phenyl-cis-1H-cyclopenta<c>pyridine

Synonyms:2-benzyloxycarbonyl-2,3,4,4a,5,6,7,7a-octahydro-5-methyl-4a-phenyl-cis-1H-cyclopentapyridine

Suppliers and Price of 2-benzyloxycarbonyl-2,3,4,4a,5,6,7,7a-octahydro-5-methyl-4a-phenyl-cis-1H-cyclopentapyridine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of 2-benzyloxycarbonyl-2,3,4,4a,5,6,7,7a-octahydro-5-methyl-4a-phenyl-cis-1H-cyclopentapyridine

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of 2-benzyloxycarbonyl-2,3,4,4a,5,6,7,7a-octahydro-5-methyl-4a-phenyl-cis-1H-cyclopentapyridine

There total 8 articles about 2-benzyloxycarbonyl-2,3,4,4a,5,6,7,7a-octahydro-5-methyl-4a-phenyl-cis-1H-cyclopentapyridine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 945-93-7,13979-22-1,1504-72-9
ethyl (E)-3-phenylbut-2-enoate

: 120402-21-3
2-benzyloxycarbonyl-2,3,4,4a,5,6,7,7a-octahydro-5-methyl-4a-phenyl-cis-1H-cyclopentapyridine

Guidance literature:: Multi-step reaction with 9 steps

1: 77 percent / 1.) lithium diisopropylamide / tetrahydrofuran / 1.) -78 deg C, 0.5 h, 2.) r.t., 2 h

2: 95 percent / LiAlH₄ / diethyl ether / 2 h

3: 73 percent / diisopropyl azodicarboxylate, triphenylphosphine / tetrahydrofuran / 14 h / Ambient temperature

4: 88 percent / NaBH₄ / methanol / 4 h

5: 63 percent / n-Bu₃P / benzene / 24 h / Ambient temperature

6: 57 percent / tri-n-butyltin hydride, azobisisobutyronitrile / benzene / 4 h / Heating

7: 1.) 10percent sodium hydroxide / 1.) ethanol, reflux, 10 h, 2.) ethanol, water, toluol, 0.5 h

8: 1.) oxalyl chloride, 2.) Et₃N / 1.) CH₂Cl₂, -78 deg C, 17 min, 2.) CH₂Cl₂, -78 deg C, 15 min, r.t., 5 min

9: 63 percent / tris(triphenylphosphine)rhodium chloride / benzene / 2 h / Heating

With sodium hydroxide; sodium tetrahydroborate; Wilkinson's catalyst; lithium aluminium tetrahydride; oxalyl dichloride; 2,2'-azobis(isobutyronitrile); tributylphosphine; di-isopropyl azodicarboxylate; tri-n-butyl-tin hydride; triethylamine; triphenylphosphine; lithium diisopropyl amide; In tetrahydrofuran; methanol; diethyl ether; benzene;

Reference yield:

: 97580-29-5
2-(1-phenylethenyl)-5-hexen-1-ol

: 120402-21-3
2-benzyloxycarbonyl-2,3,4,4a,5,6,7,7a-octahydro-5-methyl-4a-phenyl-cis-1H-cyclopentapyridine

Guidance literature:: Multi-step reaction with 7 steps

1: 73 percent / diisopropyl azodicarboxylate, triphenylphosphine / tetrahydrofuran / 14 h / Ambient temperature

2: 88 percent / NaBH₄ / methanol / 4 h

3: 63 percent / n-Bu₃P / benzene / 24 h / Ambient temperature

4: 57 percent / tri-n-butyltin hydride, azobisisobutyronitrile / benzene / 4 h / Heating

5: 1.) 10percent sodium hydroxide / 1.) ethanol, reflux, 10 h, 2.) ethanol, water, toluol, 0.5 h

6: 1.) oxalyl chloride, 2.) Et₃N / 1.) CH₂Cl₂, -78 deg C, 17 min, 2.) CH₂Cl₂, -78 deg C, 15 min, r.t., 5 min

7: 63 percent / tris(triphenylphosphine)rhodium chloride / benzene / 2 h / Heating

With sodium hydroxide; sodium tetrahydroborate; Wilkinson's catalyst; oxalyl dichloride; 2,2'-azobis(isobutyronitrile); tributylphosphine; di-isopropyl azodicarboxylate; tri-n-butyl-tin hydride; triethylamine; triphenylphosphine; In tetrahydrofuran; methanol; benzene;

Reference yield:

: 97580-25-1
ethyl 2-(1-phenylethenyl)-5-hexenoate

: 120402-21-3
2-benzyloxycarbonyl-2,3,4,4a,5,6,7,7a-octahydro-5-methyl-4a-phenyl-cis-1H-cyclopentapyridine

Guidance literature:: Multi-step reaction with 8 steps

1: 95 percent / LiAlH₄ / diethyl ether / 2 h

2: 73 percent / diisopropyl azodicarboxylate, triphenylphosphine / tetrahydrofuran / 14 h / Ambient temperature

3: 88 percent / NaBH₄ / methanol / 4 h

4: 63 percent / n-Bu₃P / benzene / 24 h / Ambient temperature

5: 57 percent / tri-n-butyltin hydride, azobisisobutyronitrile / benzene / 4 h / Heating

6: 1.) 10percent sodium hydroxide / 1.) ethanol, reflux, 10 h, 2.) ethanol, water, toluol, 0.5 h

7: 1.) oxalyl chloride, 2.) Et₃N / 1.) CH₂Cl₂, -78 deg C, 17 min, 2.) CH₂Cl₂, -78 deg C, 15 min, r.t., 5 min

8: 63 percent / tris(triphenylphosphine)rhodium chloride / benzene / 2 h / Heating

With sodium hydroxide; sodium tetrahydroborate; Wilkinson's catalyst; lithium aluminium tetrahydride; oxalyl dichloride; 2,2'-azobis(isobutyronitrile); tributylphosphine; di-isopropyl azodicarboxylate; tri-n-butyl-tin hydride; triethylamine; triphenylphosphine; In tetrahydrofuran; methanol; diethyl ether; benzene;