trans-2,6-Bis(iodomethyl)-1,4-dioxane

Base Information

• Chemical Name: trans-2,6-Bis(iodomethyl)-1,4-dioxane
• CAS No.: 6962-99-8
• Molecular Formula: C₆H₁₀I₂O₂
• Molecular Weight: 367.953
• NSC Number: 53701
• DSSTox Substance ID: DTXSID70287967
• Mol file: 6962-99-8.mol

Synonyms:2,6-bis(iodomethyl)-1,4-dioxane;6962-99-8;trans-2,6-Bis(iodomethyl)-1,4-dioxane;DTXSID70287967;NSC53701;NSC-53701

Chemical Property of trans-2,6-Bis(iodomethyl)-1,4-dioxane

Chemical Property:

• Vapor Pressure: 0.00014mmHg at 25°C
• Boiling Point: 343.4°Cat760mmHg
• Flash Point: 161.5°C
• Density: 2.185g/cm³
• XLogP3: 2
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 2
• Exact Mass: 367.87702
• Heavy Atom Count: 10
• Complexity: 89.7

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1C(OC(CO1)CI)CI

Technology Process of trans-2,6-Bis(iodomethyl)-1,4-dioxane

There total 1 articles about trans-2,6-Bis(iodomethyl)-1,4-dioxane which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

Allyl ether (557-40-4) → cis-2,6-bis-iodomethyl-[1,4]dioxane (6963-59-3) + (+/-)-trans-2,6-bis-iodomethyl-[1,4]dioxane (6962-99-8,6963-59-3)

Guidance literature:

With mercury(II) diacetate; water; Behandeln mit wss. Kaliumjodid und erwaermen des erhaltenen 2,6-Bis-jodomercuriomethyl-<1,4>dioxans mit Jod in Methanol;

DOI:10.1021/ja01632a028 DOI:10.1021/ja01558a061

Reference yield:

(+/-)-trans-2,6-bis-iodomethyl-[1,4]dioxane (6962-99-8,6963-59-3) → (+/-)-trans-2,6-bis-(benzoylamino-methyl)-[1,4]dioxane

Guidance literature:

With ammonium hydroxide; at 140 ℃; Behandeln der Reaktionsloesung mit Natriumhydroxid und Benzoylchlorid;

DOI:10.1021/ja01632a028

upstream raw materials:

Allyl ether