C₈H₁₄O₃

Base Information

• Chemical Name: C₈H₁₄O₃
• CAS No.: 1321531-29-6
• Molecular Formula: C₈H₁₄O₃
• Molecular Weight: 158.197
• Mol file: 1321531-29-6.mol

Synonyms:C₈H₁₄O₃

Chemical Property of C₈H₁₄O₃

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of C₈H₁₄O₃

There total 1 articles about C₈H₁₄O₃ which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

(1R,5S)-2-oxabicyclo[3.3.0]oct-6-en-3-one (34638-25-0,38110-77-9,43119-28-4,54483-22-6,26054-46-6) → C8H14O3 (1321531-29-6)

Guidance literature:

Multi-step reaction with 3 steps

1.1: lithium diisopropyl amide / tetrahydrofuran / 0.5 h / -78 °C / Inert atmosphere

1.2: 6 h / -78 °C / Inert atmosphere

2.1: perchloric acid; mercury(II) diacetate / tetrahydrofuran; water / 3 h / 0 °C / Inert atmosphere

2.2: 1 h / 20 °C / Inert atmosphere

2.3: 1 h / 0 °C / Inert atmosphere

3.1: diisobutylaluminium hydride / dichloromethane / 3 h / -78 °C

With perchloric acid; mercury(II) diacetate; diisobutylaluminium hydride; lithium diisopropyl amide; In tetrahydrofuran; dichloromethane; water;

DOI:10.1021/jm200649p

Reference yield:

C8H14O3 (1321531-29-6) → (3R,3aR,5R,6aR)-3-methylhexahydro-2H-cyclopenta[b]-furan-5-yl (4-nitrophenyl)carbonate (1321531-35-4)

Guidance literature:

Multi-step reaction with 2 steps

1.1: titanium tetrachloride / dichloromethane / 0.33 h / -78 °C / Inert atmosphere

1.2: 1 h / Inert atmosphere

2.1: pyridine / dichloromethane / 0 - 20 °C / Inert atmosphere

With pyridine; titanium tetrachloride; In dichloromethane;

DOI:10.1021/jm200649p

Reference yield:

C8H14O3 (1321531-29-6) → (3R,3aR,5R,6aR)-3-methylhexahydro-2H-cyclopenta[b]-furan-5-yl [(2S,3R)-3-hydroxy-4-(N-isobutyl-4-methoxyphenylsulfonamido)-1-phenylbutan-2-yl]carbamate (1321531-22-9)

Guidance literature:

Multi-step reaction with 3 steps

1.1: titanium tetrachloride / dichloromethane / 0.33 h / -78 °C / Inert atmosphere

1.2: 1 h / Inert atmosphere

2.1: pyridine / dichloromethane / 0 - 20 °C / Inert atmosphere

3.1: pyridine; trifluoroacetic acid / dichloromethane / 2 h / 20 °C / Inert atmosphere

3.2: 36 h / 0 °C / Inert atmosphere

With pyridine; titanium tetrachloride; trifluoroacetic acid; In dichloromethane;

DOI:10.1021/jm200649p

upstream raw materials:

(1R,5S)-2-oxabicyclo[3.3.0]oct-6-en-3-one

Downstream raw materials:

(3R,3aR,5R,6aR)-3-methylhexahydro-2H-cyclopenta[b]-furan-5-yl (4-nitrophenyl)carbonate

(3R,3aR,5R,6aR)-3-methylhexahydro-2H-cyclopenta[b]-furan-5-yl [(2S,3R)-3-hydroxy-4-(N-isobutyl-4-methoxyphenylsulfonamido)-1-phenylbutan-2-yl]carbamate