7-Methylbenzo[d]isoxazol-3-ol

Base Information

Chemical Name:7-Methylbenzo[d]isoxazol-3-ol
CAS No.:36238-83-2
Molecular Formula:C8H7NO2
Molecular Weight:149.149
Hs Code.:2934999090
DSSTox Substance ID:DTXSID00381947
Nikkaji Number:J3.021.462E
Wikidata:Q82173166
ChEMBL ID:CHEMBL506276
Mol file:36238-83-2.mol

Synonyms:7-methylbenzo[d]isoxazol-3-ol;36238-83-2;7-Methylbenzo[d]isoxazol-3(2H)-one;7-methyl-1,2-benzoxazol-3-one;7-methyl-1,2-benzoxazol-3-ol;3-hydroxy-7-methyl-1,2-benzisoxazole;SCHEMBL482461;CHEMBL506276;7-Methyl-benzo[d]isoxazol-3-ol;BDBM23182;AMY4956;DTXSID00381947;JUNCQBPTXAQOSA-UHFFFAOYSA-N;MFCD00104669;AKOS006229222;AKOS016002552;Benzo[d]isoxazol-3-ol Derivative, 3n;PS-4494;7-Methyl-1,2-benzoisoxazole-3(2H)-one;7-methylbenzo[d]isoxazol-3-ol, AldrichCPR;CS-0030212;FT-0621458;F17593;A874397

Suppliers and Price of 7-Methylbenzo[d]isoxazol-3-ol

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
7-Methylbenzo[d]isoxazol-3-ol
500mg
$ 110.00

SynQuest Laboratories
7-Methylbenzo[d]isoxazol-3-ol 97%
5 g
$ 448.00

Crysdot
7-Methylbenzo[d]isoxazol-3(2H)-one 95+%
5g
$ 614.00

Chemenu
7-Methylbenzo[d]isoxazol-3(2H)-one 95%
5g
$ 580.00

Apolloscientific
3-Hydroxy-7-methyl-1,2-benzisoxazole 97%
1g
$ 153.00

Apolloscientific
3-Hydroxy-7-methyl-1,2-benzisoxazole 97%
50mg
$ 29.00

American Custom Chemicals Corporation
7-METHYLBENZO[D]ISOXAZOL-3-OL 95.00%
5G
$ 1063.64

American Custom Chemicals Corporation
7-METHYLBENZO[D]ISOXAZOL-3-OL 95.00%
1G
$ 650.27

American Custom Chemicals Corporation
7-METHYLBENZO[D]ISOXAZOL-3-OL 95.00%
250MG
$ 613.88

AK Scientific
7-Methylbenzo[d]isoxazol-3(2H)-one
25g
$ 1357.00

Total 14 raw suppliers

Chemical Property of 7-Methylbenzo[d]isoxazol-3-ol

Chemical Property:

Vapor Pressure:0.000319mmHg at 25°C
Melting Point:155 °C
Refractive Index:1.574
Boiling Point:310.9 °C at 760 mmHg
PKA:13.72±0.20(Predicted)
Flash Point:141.8 °C
PSA：46.26000
Density:1.259 g/cm³
LogP:1.84180
Storage Temp.:2-8°C
XLogP3:1.5
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:0
Exact Mass:149.047678466
Heavy Atom Count:11
Complexity:181

Purity/Quality:

97% ^*data from raw suppliers

7-Methylbenzo[d]isoxazol-3-ol ^*data from reagent suppliers

Safty Information:

Pictogram(s): Xi
Hazard Codes:Xi,Xn
Statements: 36/37/38-22
Safety Statements: 26-36/37/39

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC1=C2C(=CC=C1)C(=O)NO2

Technology Process of 7-Methylbenzo[d]isoxazol-3-ol

There total 4 articles about 7-Methylbenzo[d]isoxazol-3-ol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 93.0%

: 26071-07-8
2,N-dihydroxy-3-methylbenzamide

: 36238-83-2
3-hydroxy-7-methyl-1,2-benzisoxazole

Guidance literature:: With di-isopropyl azodicarboxylate; triphenylphosphine; In tetrahydrofuran; at 20 ℃; for 0.533333h; Inert atmosphere;
DOI:10.1016/j.tetlet.2016.10.045

Reference yield:

: 83-40-9
3-methylsalicylic acid

: 36238-83-2
3-hydroxy-7-methyl-1,2-benzisoxazole

Guidance literature:: Multi-step reaction with 3 steps

1: sulfuric acid / 16 h / Reflux

2: sodium hydroxide; hydroxylamine hydrochloride / 1,4-dioxane / 16 h / 20 °C

3: triphenylphosphine; di-isopropyl azodicarboxylate / tetrahydrofuran / 0.53 h / 20 °C / Inert atmosphere

With di-isopropyl azodicarboxylate; sulfuric acid; hydroxylamine hydrochloride; triphenylphosphine; sodium hydroxide; In tetrahydrofuran; 1,4-dioxane; 3: |Mitsunobu Displacement;
DOI:10.1016/j.tetlet.2016.10.045

Reference yield:

: 23287-26-5
3-methylsalicylic acid methyl ester

: 36238-83-2
3-hydroxy-7-methyl-1,2-benzisoxazole

Guidance literature:: Multi-step reaction with 2 steps

1: sodium hydroxide; hydroxylamine hydrochloride / 1,4-dioxane / 16 h / 20 °C

2: triphenylphosphine; di-isopropyl azodicarboxylate / tetrahydrofuran / 0.53 h / 20 °C / Inert atmosphere

With di-isopropyl azodicarboxylate; hydroxylamine hydrochloride; triphenylphosphine; sodium hydroxide; In tetrahydrofuran; 1,4-dioxane; 2: |Mitsunobu Displacement;
DOI:10.1016/j.tetlet.2016.10.045