4'-Benzyloxy-2'-hydroxy-3'-methylacetophenone

Base Information

Chemical Name:4'-Benzyloxy-2'-hydroxy-3'-methylacetophenone
CAS No.:73640-74-1
Molecular Formula:C16H16 O3
Molecular Weight:256.301
Hs Code.:2914509090
European Community (EC) Number:620-874-2
DSSTox Substance ID:DTXSID00352950
Nikkaji Number:J2.241.784C
Wikidata:Q82130389
ChEMBL ID:CHEMBL1447147
Mol file:73640-74-1.mol

Synonyms:73640-74-1;4'-Benzyloxy-2'-hydroxy-3'-methylacetophenone;4'-(Benzyloxy)-2'-hydroxy-3'-methylacetophenone;1-(2-hydroxy-3-methyl-4-phenylmethoxyphenyl)ethanone;1-[4-(benzyloxy)-2-hydroxy-3-methylphenyl]ethanone;1-[4-(Benzyloxy)-2-hydroxy-3-methylphenyl]ethan-1-one;1-(4-(Benzyloxy)-2-hydroxy-3-methylphenyl)ethanone;1-(4-(Benzyloxy)-2-hydroxy-3-methylphenyl)ethan-1-one;Ethanone,1-[2-hydroxy-3-methyl-4-(phenylmethoxy)phenyl]-;MLS000439007;SCHEMBL701961;CHEMBL1447147;DTXSID00352950;PWGVUHPMXRYALX-UHFFFAOYSA-N;HMS2211K05;HMS3335G21;MFCD00010752;AKOS015913045;NCGC00090617-01;NCGC00090617-02;PS-11051;SMR000113018;CS-0455380;FT-0641477;4'-Benzyloxy-2'-hydroxy-3-methylacetophenone;A837882;1-(4-benzyloxy-2-hydroxy-3-methyl-phenyl)-ethanone;1-(3-methyl-2-oxidanyl-4-phenylmethoxy-phenyl)ethanone;1-[2-hydroxy-3-methyl-4-(phenylmethoxy)phenyl]-ethanone

Suppliers and Price of 4'-Benzyloxy-2'-hydroxy-3'-methylacetophenone

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
1-[4-(Benzyloxy)-2-hydroxy-3-methylphenyl]ethan-1-one
500mg
$ 90.00

SynQuest Laboratories
4'-(Benzyloxy)-2'-hydroxy-3'-methylacetophenone
100 mg
$ 176.00

Apolloscientific
4'-(Benzyloxy)-2'-hydroxy-3'-methylacetophenone
100mg
$ 160.00

American Custom Chemicals Corporation
4'-(BENZYLOXY)-2'-HYDROXY-3'-METHYLACETOPHENONE 95.00%
100MG
$ 737.58

AHH
4-Benzyloxy-2-hydroxy-3-methylacetophenone 98%
50g
$ 270.00

Total 8 raw suppliers

Chemical Property of 4'-Benzyloxy-2'-hydroxy-3'-methylacetophenone

Chemical Property:

Melting Point:88-90 °C(lit.)
Boiling Point:422.3oC at 760 mmHg
Flash Point:156.3oC
PSA：46.53000
Density:1.163g/cm3
LogP:3.48220
XLogP3:3.6
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:4
Exact Mass:256.109944368
Heavy Atom Count:19
Complexity:296

Purity/Quality:

97% ^*data from raw suppliers

1-[4-(Benzyloxy)-2-hydroxy-3-methylphenyl]ethan-1-one ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:Xi
Statements: 36/37/38
Safety Statements: 26-37/39

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC1=C(C=CC(=C1O)C(=O)C)OCC2=CC=CC=C2

Technology Process of 4'-Benzyloxy-2'-hydroxy-3'-methylacetophenone

There total 3 articles about 4'-Benzyloxy-2'-hydroxy-3'-methylacetophenone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 88.0%

: 10139-84-1
1-(2,4-dihydroxy-3-methylphenyl)ethanone

: 100-44-7
benzyl chloride

: 73640-74-1
1-(4-(benzyloxy)-2-hydroxy-3-methylphenyl)ethanone

Guidance literature:: With potassium carbonate; potassium iodide; In acetone; at 56 ℃;
DOI:10.1016/j.tet.2005.08.083

Reference yield:

: 608-25-3
2-methylbenzene-1,3-diol

: 73640-74-1
1-(4-(benzyloxy)-2-hydroxy-3-methylphenyl)ethanone

Guidance literature:: Multi-step reaction with 2 steps

1: 78 percent / boron trifluoride-ether complex / 6 h / 70 - 80 °C

2: 81 percent / potassium iodide, potassium carbonate / acetone / 18 h / Heating

With potassium carbonate; potassium iodide; boron trifluoride diethyl etherate; In acetone;
DOI:10.1039/P19880001823