(2R)-2-[benzyl(2-{benzyl[(2R)-1-{[bis(propan-2-yl)phosphanyl]oxy}-3-phenylpropan-2-yl]amino}ethyl)amino]-3-phenylpropyl bis(propan-2-yl)phosphinite

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Chemical Name:(2R)-2-[benzyl(2-{benzyl[(2R)-1-{[bis(propan-2-yl)phosphanyl]oxy}-3-phenylpropan-2-yl]amino}ethyl)amino]-3-phenylpropyl bis(propan-2-yl)phosphinite
CAS No.:1421593-22-7
Molecular Formula:C₄₆H₆₆N₂O₂P₂
Molecular Weight:740.99
Hs Code.:

Synonyms:(2R)-2-[benzyl(2-{benzyl[(2R)-1-{[bis(propan-2-yl)phosphanyl]oxy}-3-phenylpropan-2-yl]amino}ethyl)amino]-3-phenylpropyl bis(propan-2-yl)phosphinite

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Chemical Property of (2R)-2-[benzyl(2-{benzyl[(2R)-1-{[bis(propan-2-yl)phosphanyl]oxy}-3-phenylpropan-2-yl]amino}ethyl)amino]-3-phenylpropyl bis(propan-2-yl)phosphinite

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Technology Process of (2R)-2-[benzyl(2-{benzyl[(2R)-1-{[bis(propan-2-yl)phosphanyl]oxy}-3-phenylpropan-2-yl]amino}ethyl)amino]-3-phenylpropyl bis(propan-2-yl)phosphinite

There total 4 articles about (2R)-2-[benzyl(2-{benzyl[(2R)-1-{[bis(propan-2-yl)phosphanyl]oxy}-3-phenylpropan-2-yl]amino}ethyl)amino]-3-phenylpropyl bis(propan-2-yl)phosphinite which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 94.5%

: 19174-61-9
3-chloro-2,4-dimethylpentane

: 1421593-14-7
(2R)-2-[benzyl(2-{benzyl[(1R)-2-hydroxy-1-phenylethyl]amino}ethyl)amino]-2-phenylethan-1-ol

: 1421593-22-7
(2R)-2-[benzyl(2-{benzyl[(2R)-1-{[bis(propan-2-yl)phosphanyl]oxy}-3-phenylpropan-2-yl]amino}ethyl)amino]-3-phenylpropyl bis(propan-2-yl)phosphinite

Guidance literature:: With triethylamine; In dichloromethane; at 20 ℃; for 48h; Inert atmosphere;
DOI:10.1055/s-0032-1317505

Reference yield:

: 5267-64-1
(R)-2-amino-3-phenylpropanol

: 1421593-22-7
(2R)-2-[benzyl(2-{benzyl[(2R)-1-{[bis(propan-2-yl)phosphanyl]oxy}-3-phenylpropan-2-yl]amino}ethyl)amino]-3-phenylpropyl bis(propan-2-yl)phosphinite

Guidance literature:: Multi-step reaction with 3 steps

1: sodium carbonate / 12 h / 110 °C / Inert atmosphere

2: sodium carbonate / 12 h / 110 °C / Inert atmosphere

3: triethylamine / dichloromethane / 48 h / 20 °C / Inert atmosphere

With sodium carbonate; triethylamine; In dichloromethane;
DOI:10.1055/s-0032-1317505

Reference yield:

: 60046-47-1
(2R)-(+)-2-benzylamino-3-phenylpropan-1-ol

: 1421593-22-7
(2R)-2-[benzyl(2-{benzyl[(2R)-1-{[bis(propan-2-yl)phosphanyl]oxy}-3-phenylpropan-2-yl]amino}ethyl)amino]-3-phenylpropyl bis(propan-2-yl)phosphinite

Guidance literature:: Multi-step reaction with 2 steps

1: sodium carbonate / 12 h / 110 °C / Inert atmosphere

2: triethylamine / dichloromethane / 48 h / 20 °C / Inert atmosphere

With sodium carbonate; triethylamine; In dichloromethane;
DOI:10.1055/s-0032-1317505