3-[(4-Chlorophenyl)carbamoyl]prop-2-enoic acid

Base Information

Chemical Name:3-[(4-Chlorophenyl)carbamoyl]prop-2-enoic acid
CAS No.:306935-74-0
Molecular Formula:C10H8 Cl N O3
Molecular Weight:225.631
Hs Code.:2924299090
Mol file:306935-74-0.mol

Synonyms:3-[(4-chlorophenyl)carbamoyl]prop-2-enoic acid;114328-56-2;4'-CHLOROMALEANILIC ACID;AKOS030230144;FT-0616609;FT-0629218;(Z)-4-(4-chlorophenylamino)-4-oxobut-2-enoic acid

Suppliers and Price of 3-[(4-Chlorophenyl)carbamoyl]prop-2-enoic acid

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Atlantic Research Chemicals
4-(4-Chloroanilino)-4-oxobut-2-enoicacid 95%
250mgs:
$ 63.62

American Custom Chemicals Corporation
4-(4-CHLOROANILINO)-4-OXOBUT-2-ENOIC ACID 95.00%
1G
$ 751.91

Total 6 raw suppliers

Chemical Property of 3-[(4-Chlorophenyl)carbamoyl]prop-2-enoic acid

Chemical Property:

Vapor Pressure:1.72E-09mmHg at 25°C
Melting Point:200 °C
Boiling Point:466.2°Cat760mmHg
PKA:3.44±0.10(Predicted)
Flash Point:235.7°C
PSA：66.40000
Density:1.448g/cm³
LogP:1.99230
XLogP3:1.5
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:3
Exact Mass:225.0192708
Heavy Atom Count:15
Complexity:270

Purity/Quality:

99%, ^*data from raw suppliers

4-(4-Chloroanilino)-4-oxobut-2-enoicacid 95% ^*data from reagent suppliers

Safty Information:

Pictogram(s): R36/37/38:Irritating to eyes, respiratory system and skin.;
Hazard Codes: Xi:Irritant;
Statements: R36/37/38:Irritating to eyes, respiratory system and skin.;
Safety Statements: S26:In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.; S37/39:Wear suitable g

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CC(=CC=C1NC(=O)C=CC(=O)O)Cl

Technology Process of 3-[(4-Chlorophenyl)carbamoyl]prop-2-enoic acid

There total 1 articles about 3-[(4-Chlorophenyl)carbamoyl]prop-2-enoic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 108-31-6
maleic anhydride

: 106-47-8
4-chloro-aniline

: 306935-74-0
3-[(4-chlorophenylamido)]propenoic acid

Guidance literature:: With acetic acid; at 25 ℃; for 0.166667h;
DOI:10.1080/00304948.2013.798569

Reference yield: 83.0%

: 306935-74-0
3-[(4-chlorophenylamido)]propenoic acid

: 5970-45-6
zinc(II) acetate dihydrate

: Zn(3-[(4-chlorophenylamido)]propenoate)2]*2H₂O

Guidance literature:: In methanol; byproducts: CH3COOH; ligand dissolved in MeOH on heating at 40-50°C with stirring; soln. of Zn acetate in MeOH added dropwise; stirred for 3 h; filtered; ppt. dried in air; elem. anal.;
DOI:10.1134/S0036023611110027

Reference yield: 80.0%

: 85115-10-2,40615-17-6
3-amino-1,2,3,4-tetrahydroquinolin-2-one

: 306935-74-0
3-[(4-chlorophenylamido)]propenoic acid

: N¹-(4-chlorophenyl)-N⁴-(2-oxo-1,2,3,4-tetrahydroquinolin-3-yl)fumaramide

Guidance literature:: 3-[(4-chlorophenylamido)]propenoic acid; With iodine; triethylamine; triethyl phosphite; In dichloromethane; for 0.25h; Cooling;

3-amino-1,2,3,4-tetrahydroquinolin-2-one; In dichloromethane; at 20 ℃;
DOI:10.1016/j.ejmech.2020.112278