2-(p-chlorophenyl)-7a-hydroperoxy-4,5,6,7,7a-pentahydroindolenine

Base Information

• Chemical Name: 2-(p-chlorophenyl)-7a-hydroperoxy-4,5,6,7,7a-pentahydroindolenine
• CAS No.: 86831-07-4
• Molecular Formula: C₁₄H₁₄ClNO₂
• Molecular Weight: 263.724
• Mol file: 86831-07-4.mol

Synonyms:2-(p-chlorophenyl)-7a-hydroperoxy-4,5,6,7,7a-pentahydroindolenine

Chemical Property of 2-(p-chlorophenyl)-7a-hydroperoxy-4,5,6,7,7a-pentahydroindolenine

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 2-(p-chlorophenyl)-7a-hydroperoxy-4,5,6,7,7a-pentahydroindolenine

There total 1 articles about 2-(p-chlorophenyl)-7a-hydroperoxy-4,5,6,7,7a-pentahydroindolenine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

2-(p-chlorophenyl)-4,5,6,7-tetrahydroindole (86700-17-6) → 2-(p-chlorophenyl)-7a-hydroperoxy-4,5,6,7,7a-pentahydroindolenine (86831-07-4)

Guidance literature:

With oxygen; methylene blue; In methanol; at -50 - 0 ℃; Irradiation;

Reference yield: 100.0%

2-(p-chlorophenyl)-7a-hydroperoxy-4,5,6,7,7a-pentahydroindolenine (86831-07-4) → 2-(4-chlorophenyl)-7a-hydroxy-4,5,6,7,7a-pentahydroindolenine (86831-11-0)

Guidance literature:

With triphenylphosphine; In diethyl ether;

Reference yield:

2-(p-chlorophenyl)-7a-hydroperoxy-4,5,6,7,7a-pentahydroindolenine (86831-07-4) → 3-(4-Chloro-phenyl)-2-aza-spiro[4.4]non-3-en-1-one (86831-15-4)

Guidance literature:

Multi-step reaction with 2 steps

1: 100 percent / PPh₃ / diethyl ether / further reductant: Me₂S in MeOH

2: 0.05 h / 180 °C / further conditions: K-OtBu, DMF, -30 deg C, 1 h

With triphenylphosphine; In diethyl ether;

DOI:10.1039/c39830000355

upstream raw materials:

2-(p-chlorophenyl)-4,5,6,7-tetrahydroindole

Downstream raw materials:

2-(p-chlorophenyl)-4,5,6,7-tetrahydroindole

2-(4-chlorophenyl)-7a-hydroxy-4,5,6,7,7a-pentahydroindolenine

3-(4-Chloro-phenyl)-2-aza-spiro[4.4]non-3-en-1-one