Technology Process of 3-(3H-imidazo[4,5-b]pyridin-2-yl)-5-isopropoxyphenol
There total 5 articles about 3-(3H-imidazo[4,5-b]pyridin-2-yl)-5-isopropoxyphenol which
guide to synthetic route it.
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synthetic route:
- Guidance literature:
-
With
hydrogen;
palladium 10% on activated carbon;
In
methanol; ethyl acetate;
- Guidance literature:
-
Multi-step reaction with 3 steps
1: dmap; 3-{[(ethylimino)methylene]-amino}-N,N,N-trimethyl-1-propanaminium iodide / N,N-dimethyl-formamide / 20 °C
2: acetic acid / propyl cyanide / 2 h / 200 °C / Microwave irradiation
3: hydrogen / palladium 10% on activated carbon / methanol; ethyl acetate
With
dmap; hydrogen; 3-{[(ethylimino)methylene]-amino}-N,N,N-trimethyl-1-propanaminium iodide;
palladium 10% on activated carbon; acetic acid;
In
methanol; propyl cyanide; ethyl acetate; N,N-dimethyl-formamide;
- Guidance literature:
-
Multi-step reaction with 4 steps
1.1: methanol; sodium hydroxide; water / tetrahydrofuran / 0.75 h / Heating / reflux
1.2: pH 4
2.1: dmap; 3-{[(ethylimino)methylene]-amino}-N,N,N-trimethyl-1-propanaminium iodide / N,N-dimethyl-formamide / 20 °C
3.1: acetic acid / propyl cyanide / 2 h / 200 °C / Microwave irradiation
4.1: hydrogen / palladium 10% on activated carbon / methanol; ethyl acetate
With
methanol; dmap; sodium hydroxide; water; hydrogen; 3-{[(ethylimino)methylene]-amino}-N,N,N-trimethyl-1-propanaminium iodide;
palladium 10% on activated carbon; acetic acid;
In
tetrahydrofuran; methanol; propyl cyanide; ethyl acetate; N,N-dimethyl-formamide;
![2-[3-(benzyloxy)-5-isopropoxyphenyl]-3H-imidazo[4,5-b]pyridine](/Databaselist/images/loading.webp)
