2-Methylthiazole-4-carbothioamide

Base Information

Chemical Name:2-Methylthiazole-4-carbothioamide
CAS No.:174223-29-1
Molecular Formula:C₅H₆N₂S₂
Molecular Weight:158.248
Hs Code.:2934100090
DSSTox Substance ID:DTXSID10372528
Nikkaji Number:J2.185.522G
Wikidata:Q72491227
Mol file:174223-29-1.mol

Synonyms:2-methylthiazole-4-carbothioamide;174223-29-1;2-methyl-1,3-thiazole-4-carbothioamide;C5H6N2S2;MFCD00052167;2-Methyl-thiazole-4-carbothioic acid amide;4-Thiazolecarbothioamide, 2-methyl-;Maybridge4_004334;SCHEMBL5046969;SCHEMBL12849239;DTXSID10372528;DIOPPULTIGEDCB-UHFFFAOYSA-N;2-methylthiazole-4-thiocarboxamide;HMS1533E22;STR07268;CCG-50871;AKOS005257109;2-Methylthiazole-4-carbothioic acid amide;CS-0282272;FT-0612889;FT-0620318;EN300-1828026;2-methyl-1,3-thiazole-4-carbothioamide, AldrichCPR;SR-01000640212-1;BRD-K51912942-001-01-8

Suppliers and Price of 2-Methylthiazole-4-carbothioamide

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
2-Methylthiazole-4-carbothioamide
500mg
$ 240.00

TRC
2-Methylthiazole-4-carbothioamide
50mg
$ 45.00

Matrix Scientific
2-Methyl-thiazole-4-carbothioicacidamide 95%+
1g
$ 126.00

Matrix Scientific
2-Methyl-thiazole-4-carbothioicacidamide 95%+
10g
$ 1008.00

Matrix Scientific
2-Methyl-thiazole-4-carbothioicacidamide 95%+
5g
$ 540.00

Crysdot
2-Methylthiazole-4-carbothioamide 95+%
10g
$ 455.00

Chemenu
2-methylthiazole-4-carbothioamide 95%
1g
$ 248.00

Atlantic Research Chemicals
2-Methyl-1,3-thiazole-4-carbothioamide 95%
1gm:
$ 81.29

American Custom Chemicals Corporation
2-METHYL-1,3-THIAZOLE-4-CARBOTHIOAMIDE 95.00%
1G
$ 248.89

American Custom Chemicals Corporation
2-METHYL-1,3-THIAZOLE-4-CARBOTHIOAMIDE 95.00%
5G
$ 1088.38

Total 31 raw suppliers

Chemical Property of 2-Methylthiazole-4-carbothioamide

Chemical Property:

Vapor Pressure:0.002mmHg at 25°C
Melting Point:201 °C
Refractive Index:1.686
Boiling Point:289.621 °C at 760 mmHg
Flash Point:128.959 °C
PSA：99.24000
Density:1.376 g/cm³
LogP:1.78600
Storage Temp.:2-8°C
XLogP3:1.2
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:1
Exact Mass:157.99724055
Heavy Atom Count:9
Complexity:126

Purity/Quality:

97% ^*data from raw suppliers

2-Methylthiazole-4-carbothioamide ^*data from reagent suppliers

Safty Information:

Pictogram(s): Xi
Hazard Codes:Xi,Xn
Statements: 36/37/38-41-37/38-22
Safety Statements: 26-36/37/39-39

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC1=NC(=CS1)C(=S)N

Technology Process of 2-Methylthiazole-4-carbothioamide

There total 2 articles about 2-Methylthiazole-4-carbothioamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 6436-59-5
ethyl 2-methylthiazole-4-carboxylate

: 174223-29-1
2-methyl-1,3-thiazole-4-carbothioamide

Guidance literature:: Multi-step reaction with 2 steps

1: ammonium hydroxide / water / 2 h / 70 °C

2: Lawessons reagent / toluene / 2 h / Reflux

With Lawessons reagent; ammonium hydroxide; In water; toluene;
DOI:10.1021/ja110166x

Reference yield:

: 31825-95-3
2-methylthiazole-4-carboxamide

: 174223-29-1
2-methyl-1,3-thiazole-4-carbothioamide

Guidance literature:: With Lawessons reagent; In toluene; for 2h; Reflux; Inert atmosphere;
DOI:10.1021/jo900950x

Reference yield:

: 174223-29-1
2-methyl-1,3-thiazole-4-carbothioamide

: C₃₇H₃₇N₃O₃S₃

Guidance literature:: Multi-step reaction with 4 steps

1.1: potassium hydrogencarbonate / 1,2-dimethoxyethane / 0.17 h / 20 °C

1.2: 12.67 h / 0 - 20 °C

2.1: lithium hydroxide; water / ethanol / 12 h / 0 - 20 °C

3.1: 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; benzotriazol-1-ol; N-ethyl-N,N-diisopropylamine / N,N-dimethyl-formamide / 12 h / 20 °C

4.1: tricyclohexylphosphine[1,3-bis(2,4,6-trimethylphenyl)-4,5-dihydroimidazol-2-ylidine][benzylidene]ruthenium(II) dichloride / toluene / 8 h / 110 °C

With tricyclohexylphosphine[1,3-bis(2,4,6-trimethylphenyl)-4,5-dihydroimidazol-2-ylidine][benzylidene]ruthenium(II) dichloride; water; benzotriazol-1-ol; potassium hydrogencarbonate; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; N-ethyl-N,N-diisopropylamine; lithium hydroxide; In 1,2-dimethoxyethane; ethanol; N,N-dimethyl-formamide; toluene;
DOI:10.1021/ml400470s