Ethyl 2,4-dioxo-4-(thiophen-2-yl)butanoate

Base Information

Chemical Name:Ethyl 2,4-dioxo-4-(thiophen-2-yl)butanoate
CAS No.:36983-36-5
Molecular Formula:C10H10 O4 S
Molecular Weight:226.253
Hs Code.:2934999090
DSSTox Substance ID:DTXSID80384072
Nikkaji Number:J2.623.599E
Wikidata:Q82175989
Mol file:36983-36-5.mol

Synonyms:36983-36-5;ethyl 2,4-dioxo-4-(thiophen-2-yl)butanoate;ethyl 2,4-dioxo-4-(2-thienyl)butanoate;ethyl 2,4-dioxo-4-thiophen-2-ylbutanoate;2,4-Dioxo-4-thiophen-2-yl-butyric acid ethyl ester;SCHEMBL1694502;DTXSID80384072;MFCD00126316;AKOS000210787;AS-5237;Ethyl 2,4-dioxo-4-(thien-2-yl)butanoate;FT-0625892;2,4-Dioxo-4-(2-thienyl)butanoic acid ethyl ester;2,4-Dioxo-4-thiophen-2-ylbutyric acid ethyl ester

Suppliers and Price of Ethyl 2,4-dioxo-4-(thiophen-2-yl)butanoate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
2,4-Dioxo-4-thiophen-2-yl-butyricAcidEthylEster
500mg
$ 65.00

TRC
2,4-Dioxo-4-thiophen-2-yl-butyricAcidEthylEster
100mg
$ 45.00

SynQuest Laboratories
Ethyl 2,4-dioxo-4-(thien-2-yl)butanoate
1 g
$ 40.00

SynQuest Laboratories
Ethyl 2,4-dioxo-4-(thien-2-yl)butanoate
5 g
$ 136.00

Matrix Scientific
2,4-Dioxo-4-thiophen-2-yl-butyric acid ethyl ester tech
5g
$ 303.00

Crysdot
Ethyl2,4-dioxo-4-(thiophen-2-yl)butanoate 95+%
10g
$ 425.00

Chemenu
Ethyl2,4-dioxo-4-(thiophen-2-yl)butanoate 95%
10g
$ 401.00

Atlantic Research Chemicals
Ethyl2,4-Dioxo-4-(2-thienyl)butanoate 95%
1gm:
$ 38.88

Arctom
Ethyl2,4-dioxo-4-(thiophen-2-yl)butanoate ≥95%
1g
$ 38.00

Arctom
Ethyl2,4-dioxo-4-(thiophen-2-yl)butanoate ≥95%
5g
$ 113.00

Total 13 raw suppliers

Chemical Property of Ethyl 2,4-dioxo-4-(thiophen-2-yl)butanoate

Chemical Property:

Vapor Pressure:7.52E-06mmHg at 25°C
Melting Point:34°C
Boiling Point:375.9°Cat760mmHg
Flash Point:181.1°C
PSA：88.68000
Density:1.277g/cm³
LogP:1.45310
XLogP3:1.9
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:6
Exact Mass:226.02997997
Heavy Atom Count:15
Complexity:275

Purity/Quality:

99%, ^*data from raw suppliers

2,4-Dioxo-4-thiophen-2-yl-butyricAcidEthylEster ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:Xi
Safety Statements: S24/25:Avoid contact with skin and eyes.;

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CCOC(=O)C(=O)CC(=O)C1=CC=CS1

Technology Process of Ethyl 2,4-dioxo-4-(thiophen-2-yl)butanoate

There total 4 articles about Ethyl 2,4-dioxo-4-(thiophen-2-yl)butanoate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

: 88-15-3,97511-16-5
2-Acetylthiophene

: 95-92-1
oxalic acid diethyl ester

: 36983-36-5
ethyl 2,4-dioxo-4-(thiophen-2-yl)butanoate

Guidance literature:: With sodium ethanolate; In ethanol; at 0 - 20 ℃; for 20h;
DOI:10.1016/S0960-894X(00)00513-8

Reference yield: 87.0%

: 36983-36-5
ethyl 2,4-dioxo-4-(thiophen-2-yl)butanoate

Guidance literature:: With sodium; In ethanol; for 16h; Cooling with ice;

Reference yield:

: 5370-25-2
2-Acetyl-5-bromothiophene

: 36983-36-5
ethyl 2,4-dioxo-4-(thiophen-2-yl)butanoate

Guidance literature:: Multi-step reaction with 2 steps

1: toluene-4-sulfonic acid / ethylene glycol; toluene / Reflux

2: potassium tert-butylate / toluene / 0 - 20 °C

With potassium tert-butylate; toluene-4-sulfonic acid; In ethylene glycol; toluene;
DOI:10.1002/chem.201102571