(1'S,2'R,3'S,4'R)-3-phenyl-6[(3'-hydroxy-1',2',4',5'-diisopropylidenedioxy)pentyl]-uracil

Base Information

• Chemical Name: (1'S,2'R,3'S,4'R)-3-phenyl-6[(3'-hydroxy-1',2',4',5'-diisopropylidenedioxy)pentyl]-uracil
• CAS No.: 1192310-41-0
• Molecular Formula: C₂₁H₂₆N₂O₇
• Molecular Weight: 418.447
• Mol file: 1192310-41-0.mol

Synonyms:(1'S,2'R,3'S,4'R)-3-phenyl-6[(3'-hydroxy-1',2',4',5'-diisopropylidenedioxy)pentyl]-uracil

Chemical Property of (1'S,2'R,3'S,4'R)-3-phenyl-6[(3'-hydroxy-1',2',4',5'-diisopropylidenedioxy)pentyl]-uracil

Chemical Property:

Purity/Quality:

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MSDS Files:

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Technology Process of (1'S,2'R,3'S,4'R)-3-phenyl-6[(3'-hydroxy-1',2',4',5'-diisopropylidenedioxy)pentyl]-uracil

There total 1 articles about (1'S,2'R,3'S,4'R)-3-phenyl-6[(3'-hydroxy-1',2',4',5'-diisopropylidenedioxy)pentyl]-uracil which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 60.0%

3-phenyl-1-[methyl 2,3-dideoxy-4,5:7,8-di-O-isopropylidene-D-gulo-3-octulofuranoate-3-yl]-urea (1192310-38-5) → (1'S,2'R,3'S,4'R)-3-phenyl-6[(3'-hydroxy-1',2',4',5'-diisopropylidenedioxy)pentyl]-uracil (1192310-41-0)

Guidance literature:

With tetrabutyl ammonium fluoride; In tetrahydrofuran; at 20 ℃; for 48h;

DOI:10.1021/jo901604w

Reference yield:

(1'S,2'R,3'S,4'R)-3-phenyl-6[(3'-hydroxy-1',2',4',5'-diisopropylidenedioxy)pentyl]-uracil (1192310-41-0) + acetic anhydride (108-24-7) → (1'S,2'R,3'S,4'R)-3-phenyl-6[(3'-acetoxy-1',2',4',5'-diisopropylidenedioxy)pentyl]-uracil (1192310-42-1)

Guidance literature:

With pyridine; at 20 ℃; for 4h;

DOI:10.1021/jo901604w

upstream raw materials:

3-phenyl-1-[methyl 2,3-dideoxy-4,5:7,8-di-O-isopropylidene-D-gulo-3-octulofuranoate-3-yl]-urea

Downstream raw materials:

(1'S,2'R,3'S,4'R)-3-phenyl-6[(3'-acetoxy-1',2',4',5'-diisopropylidenedioxy)pentyl]-uracil