p-(4-fluorobicyclo<2.2.2>oct-1-yl)phenyltrimethylammonium chloride

Base Information

Chemical Name:p-(4-fluorobicyclo<2.2.2>oct-1-yl)phenyltrimethylammonium chloride
CAS No.:81689-02-3
Molecular Formula:C₁₇H₂₅FN*Cl
Molecular Weight:297.844
Hs Code.:

Synonyms:p-(4-fluorobicyclo<2.2.2>oct-1-yl)phenyltrimethylammonium chloride

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of p-(4-fluorobicyclo<2.2.2>oct-1-yl)phenyltrimethylammonium chloride

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Technology Process of p-(4-fluorobicyclo<2.2.2>oct-1-yl)phenyltrimethylammonium chloride

There total 2 articles about p-(4-fluorobicyclo<2.2.2>oct-1-yl)phenyltrimethylammonium chloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 81.0%

: 81689-01-2
p-(4-fluorobicyclo<2.2.2>oct-1-yl)phenyltrimethylammonium iodide

: 81689-02-3
p-(4-fluorobicyclo<2.2.2>oct-1-yl)phenyltrimethylammonium chloride

Guidance literature:: With Amberlite IRA-400 resin; In methanol;
DOI:10.1021/jo00136a027

Reference yield:

: 60526-67-2
1-fluoro-4-(4-aminophenyl)bicyclo<2.2.2>octane

: 81689-02-3
p-(4-fluorobicyclo<2.2.2>oct-1-yl)phenyltrimethylammonium chloride

Guidance literature:: Multi-step reaction with 2 steps

1: 77 percent / anhydrous K₂CO₃ / acetone / 72 h / Heating

2: 81 percent / Amberlite IRA-400 resin / methanol

With Amberlite IRA-400 resin; potassium carbonate; In methanol; acetone;
DOI:10.1021/jo00136a027