Technology Process of C38H44N6O8
There total 9 articles about C38H44N6O8 which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
Multi-step reaction with 2 steps
1: dicyclohexyl-carbodiimide; 1-hydroxy-pyrrolidine-2,5-dione; sodium hydrogencarbonate / tetrahydrofuran; water / 0 - 20 °C / pH 9 - 10
2: N-ethyl-N,N-diisopropylamine; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; benzotriazol-1-ol / dichloromethane / 0 - 20 °C
With
1-hydroxy-pyrrolidine-2,5-dione; sodium hydrogencarbonate; benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; N-ethyl-N,N-diisopropylamine; dicyclohexyl-carbodiimide;
In
tetrahydrofuran; dichloromethane; water;
DOI:10.1021/jm400195y
- Guidance literature:
-
With
benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; N-ethyl-N,N-diisopropylamine;
In
dichloromethane;
at 0 - 20 ℃;
DOI:10.1021/jm400195y
- Guidance literature:
-
Multi-step reaction with 6 steps
1.1: sodium methylate / tetrahydrofuran; methanol / 0.5 h / 0 °C
1.2: 18 h / -10 °C / Enzymatic reaction
2.1: lithium hydroxide; water / tetrahydrofuran / 3 h / 20 °C
3.1: hydrogenchloride / ethyl acetate
4.1: N-ethyl-N,N-diisopropylamine; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; benzotriazol-1-ol / dichloromethane / 0 - 20 °C
5.1: hydrogenchloride / ethyl acetate
6.1: N-ethyl-N,N-diisopropylamine; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; benzotriazol-1-ol / dichloromethane / 0 - 20 °C
With
hydrogenchloride; water; sodium methylate; benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; N-ethyl-N,N-diisopropylamine; lithium hydroxide;
In
tetrahydrofuran; methanol; dichloromethane; ethyl acetate;
DOI:10.1021/jm400195y