tert-butyl (R)-3-((S)-4-benzyl-2-oxooxazolidin-3-yl)-2-(4-chlorophenyl)-3-oxopropyl(isopropyl)carbamate

Base Information

Chemical Name:tert-butyl (R)-3-((S)-4-benzyl-2-oxooxazolidin-3-yl)-2-(4-chlorophenyl)-3-oxopropyl(isopropyl)carbamate
CAS No.:1001179-29-8
Molecular Formula:C₂₇H₃₃ClN₂O₅
Molecular Weight:501.022
Hs Code.:

Synonyms:tert-butyl (R)-3-((S)-4-benzyl-2-oxooxazolidin-3-yl)-2-(4-chlorophenyl)-3-oxopropyl(isopropyl)carbamate

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Chemical Property of tert-butyl (R)-3-((S)-4-benzyl-2-oxooxazolidin-3-yl)-2-(4-chlorophenyl)-3-oxopropyl(isopropyl)carbamate

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Technology Process of tert-butyl (R)-3-((S)-4-benzyl-2-oxooxazolidin-3-yl)-2-(4-chlorophenyl)-3-oxopropyl(isopropyl)carbamate

There total 10 articles about tert-butyl (R)-3-((S)-4-benzyl-2-oxooxazolidin-3-yl)-2-(4-chlorophenyl)-3-oxopropyl(isopropyl)carbamate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 24.0%

: C₂₂H₃₂ClNO₅

: 90719-32-7
(S)-4-Benzyl-2-oxazolidinone

: 1001179-31-2
tert-butyl (S)-3-((S)-4-benzyl-2-oxooxazolidin-3-yl)-2-(4-chlorophenyl)-3-oxopropyl(isopropyl)carbamate

: 1001179-29-8
tert-butyl (R)-3-((S)-4-benzyl-2-oxooxazolidin-3-yl)-2-(4-chlorophenyl)-3-oxopropyl(isopropyl)carbamate

Guidance literature:: (S)-4-Benzyl-2-oxazolidinone; With n-butyllithium; In tetrahydrofuran; hexane; at -78 ℃; for 1h;

C₂₂H₃₂ClNO₅; In tetrahydrofuran; hexane; at -78 - 20 ℃;

With water; ammonium chloride; In tetrahydrofuran; hexane;

Reference yield: 24.0%

: C₂₂H₃₂ClNO₅

: 1001179-31-2
tert-butyl (S)-3-((S)-4-benzyl-2-oxooxazolidin-3-yl)-2-(4-chlorophenyl)-3-oxopropyl(isopropyl)carbamate

: 1001179-29-8
tert-butyl (R)-3-((S)-4-benzyl-2-oxooxazolidin-3-yl)-2-(4-chlorophenyl)-3-oxopropyl(isopropyl)carbamate

Guidance literature:: (S)-4-Benzyl-2-oxazolidinone; With n-butyllithium; In tetrahydrofuran; hexanes; at -78 ℃; for 1h;

C₂₂H₃₂ClNO₅; In tetrahydrofuran; hexanes; at -78 - 20 ℃;

With water; ammonium chloride; In tetrahydrofuran; hexanes;

Reference yield: 24.0%

: 1001179-27-6
potassium 3-(tert-butoxycarbonyl(isopropyl)amino)-2-(4-chlorophenyl)propanoate

: 90719-32-7
(S)-4-Benzyl-2-oxazolidinone

: 1001179-31-2
tert-butyl (S)-3-((S)-4-benzyl-2-oxooxazolidin-3-yl)-2-(4-chlorophenyl)-3-oxopropyl(isopropyl)carbamate

: 1001179-29-8
tert-butyl (R)-3-((S)-4-benzyl-2-oxooxazolidin-3-yl)-2-(4-chlorophenyl)-3-oxopropyl(isopropyl)carbamate

Guidance literature:: potassium 3-(tert-butoxycarbonyl(isopropyl)amino)-2-(4-chlorophenyl)propanoate; With pivaloyl chloride; In tetrahydrofuran; at 20 ℃; for 3h;

(S)-4-Benzyl-2-oxazolidinone; With n-butyllithium; In tetrahydrofuran; hexane; at 20 ℃;