2-Nitrobenzo[f]quinoline

Base Information

• Chemical Name: 2-Nitrobenzo[f]quinoline
• CAS No.: 91804-76-1
• Molecular Formula: C₁₃H₈N₂O₂
• Molecular Weight: 224.219
• NSC Number: 77611
• DSSTox Substance ID: DTXSID20291731
• Wikidata: Q82029773
• ChEMBL ID: CHEMBL1373456
• Mol file: 91804-76-1.mol

Synonyms:2-nitrobenzo[f]quinoline;91804-76-1;2-Nitrobenzo(f)quinoline;NSC 77611;HMS2896J19;NSC77611;NCIOpen2_004701;MLS001193281;CHEMBL1373456;DTXSID20291731;NSC-77611;AKOS033718852;SMR000592299;Z199055466

Chemical Property of 2-Nitrobenzo[f]quinoline

Chemical Property:

• Vapor Pressure: 5.84E-07mmHg at 25°C
• XLogP3: 3.2
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 3
• Rotatable Bond Count: 0
• Exact Mass: 224.058577502
• Heavy Atom Count: 17
• Complexity: 302

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

• Canonical SMILES: C1=CC=C2C(=C1)C=CC3=C2C=C(C=N3)[N+](=O)[O-]

Technology Process of 2-Nitrobenzo[f]quinoline

There total 2 articles about 2-Nitrobenzo[f]quinoline which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

→ 2-nitro-benzo[f]quinoline (91804-76-1)

Guidance literature:

With zinc(II) chloride; at 220 ℃; Erhitzen des Reaktionsprodukts mit wss.Salzsaeure_.;

DOI:10.1021/jo01177a014

Reference yield:

→ 2-nitro-benzo[f]quinoline (91804-76-1)

Guidance literature:

N-<2-Nitro-propyliden-3-on>-2-amino-naphthalin, Polyphosphorsaeure, 140gradC;

Reference yield:

2-nitro-benzo[f]quinoline (91804-76-1) → benzo[f]quinoline (85-02-9)

Guidance literature:

Multi-step reaction with 2 steps

1: platinum; ethanol / Hydrogenation

2: acetic acid; sodium nitrite; concentrated H₂SO₄ / anschl. mit Kupfer(I)-oxid und Aethanol

With ethanol; sulfuric acid; acetic acid; platinum; sodium nitrite;

DOI:10.1021/jo01177a014

Downstream raw materials:

benzo[f]quinolin-2-amine

benzo[f]quinoline