5-hydroxy-5-trimethylsilanylethynyl-cyclohex-1-enecarboxylic acid methyl ester

Base Information

Chemical Name:5-hydroxy-5-trimethylsilanylethynyl-cyclohex-1-enecarboxylic acid methyl ester
CAS No.:156826-19-6
Molecular Formula:C₁₃H₂₀O₃Si
Molecular Weight:252.386
Hs Code.:

Synonyms:5-hydroxy-5-trimethylsilanylethynyl-cyclohex-1-enecarboxylic acid methyl ester

Suppliers and Price of 5-hydroxy-5-trimethylsilanylethynyl-cyclohex-1-enecarboxylic acid methyl ester

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of 5-hydroxy-5-trimethylsilanylethynyl-cyclohex-1-enecarboxylic acid methyl ester

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of 5-hydroxy-5-trimethylsilanylethynyl-cyclohex-1-enecarboxylic acid methyl ester

There total 1 articles about 5-hydroxy-5-trimethylsilanylethynyl-cyclohex-1-enecarboxylic acid methyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 66838-90-2
5-Oxo-1-cyclohexenecarboxylic acid methyl ester

: 1066-54-2
trimethylsilylacetylene

: 156826-19-6
5-hydroxy-5-trimethylsilanylethynyl-cyclohex-1-enecarboxylic acid methyl ester

Guidance literature:: With cerium(III) chloride; lithium hexamethyldisilazane; Yield given. Multistep reaction; 1.) tetrahydrofuran, -78 deg C, 30 min, 2.) tetrahydrofuran, -78 deg C, 5 min, 3.) tetrahydrofuran, -78 deg C, 20 min;
DOI:10.1016/S0040-4020(01)80632-3

Reference yield: 97.0%

: 69739-34-0
t-butyldimethylsiyl triflate

: 156826-19-6
5-hydroxy-5-trimethylsilanylethynyl-cyclohex-1-enecarboxylic acid methyl ester

: 156826-20-9
5-<(tert-butyldimethylsilyl)oxy>-5-trimethylsilanylethynyl-cyclohex-1-enecarboxylic acid methyl ester

Guidance literature:: With 2,6-dimethylpyridine; In dichloromethane; for 5h;
DOI:10.1016/S0040-4020(01)80632-3

Reference yield:

: 156826-19-6
5-hydroxy-5-trimethylsilanylethynyl-cyclohex-1-enecarboxylic acid methyl ester

: 156826-22-1
4-ethynyl-2-hydroxymethyl-4-<(tert-butyldimethylsilyl)oxy>-cyclohex-1-ene

Guidance literature:: Multi-step reaction with 3 steps

1: 97 percent / 2,6-lutidine / CH₂Cl₂ / 5 h

2: 100 percent / 1.0M diisobutylaluminumhydride in hexane / CH₂Cl₂ / 0.17 h / -78 °C

3: 99 percent / potassium carbonate / methanol / 16 h / 25 °C

With 2,6-dimethylpyridine; diisobutylaluminium hydride; potassium carbonate; In methanol; dichloromethane;
DOI:10.1016/S0040-4020(01)80632-3