N-[2-(cyclopent-2-en-1-yl)-4-methylphenyl]-4-methylbenzenesulfonamide

Base Information

• Chemical Name: N-[2-(cyclopent-2-en-1-yl)-4-methylphenyl]-4-methylbenzenesulfonamide
• CAS No.: 1394828-32-0
• Molecular Formula: C₁₉H₂₁NO₂S
• Molecular Weight: 327.447
• Mol file: 1394828-32-0.mol

Synonyms:N-[2-(cyclopent-2-en-1-yl)-4-methylphenyl]-4-methylbenzenesulfonamide

Chemical Property of N-[2-(cyclopent-2-en-1-yl)-4-methylphenyl]-4-methylbenzenesulfonamide

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of N-[2-(cyclopent-2-en-1-yl)-4-methylphenyl]-4-methylbenzenesulfonamide

There total 1 articles about N-[2-(cyclopent-2-en-1-yl)-4-methylphenyl]-4-methylbenzenesulfonamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 82.0%

4-methyl-2-(cyclopent-2-en-1-yl)aniline (84487-49-0) + p-toluenesulfonyl chloride (98-59-9) → N-[2-(cyclopent-2-en-1-yl)-4-methylphenyl]-4-methylbenzenesulfonamide (1394828-32-0)

Guidance literature:

With triethylamine; In benzene; at 20 ℃; for 48h;

DOI:10.1134/S1070428012070123

Reference yield: 83.0%

N-[2-(cyclopent-2-en-1-yl)-4-methylphenyl]-4-methylbenzenesulfonamide (1394828-32-0) → 3-iodo-4-methylphenylsulfonyl-7-methyl-1,2,3,3a,4,8b-hexahydrocyclopenta[b]indole

Guidance literature:

With iodine; sodium hydrogencarbonate; In dichloromethane; at 20 ℃; for 48h;

DOI:10.1134/S1070428012070123

Reference yield:

N-[2-(cyclopent-2-en-1-yl)-4-methylphenyl]-4-methylbenzenesulfonamide (1394828-32-0) → 7-methyl-4-(4-methylphenylsulfonyl)-1,2,3,3a,4,8b-hexahydrocyclopenta[b]indole-2,3-diol

Guidance literature:

Multi-step reaction with 3 steps

1: iodine; sodium hydrogencarbonate / dichloromethane / 48 h / 20 °C

2: piperidine / 10 h / 110 °C

3: potassium permanganate / methanol; water; acetonitrile / 6 h / 20 °C

With piperidine; potassium permanganate; iodine; sodium hydrogencarbonate; In methanol; dichloromethane; water; acetonitrile;

DOI:10.1134/S1070428012070123

upstream raw materials:

4-methyl-2-(cyclopent-2-en-1-yl)aniline

p-toluenesulfonyl chloride