5,11,17,23-tetra-tert-butyl-25-(4-formyl-2-nitrophenoxy)calix[4]arene-26,27,28-triol

Base Information

• Chemical Name: 5,11,17,23-tetra-tert-butyl-25-(4-formyl-2-nitrophenoxy)calix[4]arene-26,27,28-triol
• CAS No.: 368427-56-9
• Molecular Formula: C₅₁H₅₉NO₇
• Molecular Weight: 798.032
• Mol file: 368427-56-9.mol

Synonyms:5,11,17,23-tetra-tert-butyl-25-(4-formyl-2-nitrophenoxy)calix[4]arene-26,27,28-triol

Chemical Property of 5,11,17,23-tetra-tert-butyl-25-(4-formyl-2-nitrophenoxy)calix[4]arene-26,27,28-triol

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 5,11,17,23-tetra-tert-butyl-25-(4-formyl-2-nitrophenoxy)calix[4]arene-26,27,28-triol

There total 2 articles about 5,11,17,23-tetra-tert-butyl-25-(4-formyl-2-nitrophenoxy)calix[4]arene-26,27,28-triol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 58.0%

5,11,17,23-tetra-t-butyl-25,26,27,28-tetrahydroxycalix-4-arene (157432-87-6,288302-11-4,288302-12-5,60705-62-6) + 4-fluoro-3-nitrobenzaldehyde (42564-51-2) → 5,11,17,23-tetra-tert-butyl-25-(4-formyl-2-nitrophenoxy)calix[4]arene-26,27,28-triol (368427-56-9)

Guidance literature:

With potassium carbonate; In N,N-dimethyl-formamide; at 20 ℃; for 120h;

DOI:10.1021/jo015622x

Reference yield: 38.0%

5,11,17,23-tetra-t-butyl-25,26,27,28-tetrahydroxycalix-4-arene (157432-87-6,288302-11-4,288302-12-5,60705-62-6) + 4-fluoro-3-nitrobenzaldehyde (42564-51-2) → 5,11,17,23-tetra-tert-butyl-25-(4-formyl-2-nitrophenoxy)calix[4]arene-26,27,28-triol (368427-56-9) + 5,11,17,23-tetra-tert-butyl-25,27-di(4-formyl-2-nitrophenoxy)calix[4]arene-26,28-diol

Guidance literature:

With pyridine; potassium carbonate; copper(II) oxide; for 48h; Heating;

DOI:10.1021/jo015622x

Reference yield: 87.0%

5,11,17,23-tetra-tert-butyl-25-(4-formyl-2-nitrophenoxy)calix[4]arene-26,27,28-triol (368427-56-9) → 5,11,17,23-tetra-tert-butyl-25-(4-hydroxymethyl-2-nitrophenoxy)calix[4]arene-26,27,28-triol

Guidance literature:

With sodium tetrahydroborate; In methanol; at 20 ℃; for 2h;

DOI:10.1021/jo015622x

upstream raw materials:

5,11,17,23-tetra-t-butyl-25,26,27,28-tetrahydroxycalix-4-arene

4-fluoro-3-nitrobenzaldehyde