2-[(4-trifluoromethylphenyl)ethynyl]benzoxazole

Base Information

• Chemical Name: 2-[(4-trifluoromethylphenyl)ethynyl]benzoxazole
• CAS No.: 1187772-37-7
• Molecular Formula: C₁₆H₈F₃NO
• Molecular Weight: 287.241

Synonyms:2-[(4-trifluoromethylphenyl)ethynyl]benzoxazole

Chemical Property of 2-[(4-trifluoromethylphenyl)ethynyl]benzoxazole

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 2-[(4-trifluoromethylphenyl)ethynyl]benzoxazole

There total 5 articles about 2-[(4-trifluoromethylphenyl)ethynyl]benzoxazole which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 60.0%

1-(bromoethynyl)-4-(trifluoromethyl)benzene (313343-88-3) + benzoxazole (273-53-0,29791-96-6) → 2-[(4-trifluoromethylphenyl)ethynyl]benzoxazole (1187772-37-7)

Guidance literature:

With bis(1,5-cyclooctadiene)nickel⁽⁰⁾; o-phenylenebis(diphenylphosphine); lithium tert-butoxide; In toluene; for 1h; Reflux; Inert atmosphere;

DOI:10.1021/ol901684h

Reference yield: 43.0%

benzoxazole (273-53-0,29791-96-6) + 4-trifluoromethylphenylacetylene (705-31-7) → 2-[(4-trifluoromethylphenyl)ethynyl]benzoxazole (1187772-37-7)

Guidance literature:

With nickel(II) bromide diethylene glycol dimethyl ether; oxygen; 4,4'-di-tert-butyl-2,2'-bipyridine; lithium tert-butoxide; In toluene; at 100 ℃; for 1h; under 760.051 Torr;

DOI:10.1021/ol100699g

Reference yield: 19.0%

2-methylsulfanyl-benzoxazole (13673-62-6) + 4-trifluoromethylphenylacetylene (705-31-7) → 2-[(4-trifluoromethylphenyl)ethynyl]benzoxazole (1187772-37-7)

Guidance literature:

With (1,1'-bis(diphenylphosphino)ferrocene)palladium(II) dichloride; copper(l) iodide; triethylamine; In toluene; for 24h; Reflux;

DOI:10.1016/j.tetlet.2015.08.001

upstream raw materials:

1-(bromoethynyl)-4-(trifluoromethyl)benzene

benzoxazole

4-trifluoromethylphenylacetylene

1-(2,2-dibromovinyl)-4-(trifluoromethyl)benzeney

Post a RFQ

Cas No.:

Product Name:

Quantity:

Please select Metric Ton KG G Pound L ML

Email:

Company name:

Valid Period:

Detailed Requirements:

• Sample
• MOQ
• GMP
• FDA
• Price
  FOB CIF CFR EXW
• Urgent purchase

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

Remove

Submit

1

What can I do for you?
Get Best Price

Get Best Price for 1187772-37-7 2-[(4-trifluoromethylphenyl)ethynyl]benzoxazole

Send

Send

Metric Ton KG G Pound L ML

Send

Send