4-aniline

Base Information

Chemical Name:4-aniline
CAS No.:85010-82-8
Molecular Formula:C₂₁H₂₂N₂O₂S
Molecular Weight:366.484
Hs Code.:

4-<N-phenethyl-N-(p-toluenesulphonyl)amino>aniline

Synonyms:4-aniline

Suppliers and Price of 4-aniline

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Total 0 raw suppliers

Chemical Property of 4-aniline

Chemical Property:

Purity/Quality:

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Technology Process of 4-aniline

There total 1 articles about 4-aniline which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 74.6%

: 6380-08-1
N-(4-aminophenyl)-4-methylbenzenesulfonamide

: 103-63-9
1-phenyl-2-bromoethane

: 85010-82-8
4-aniline

Guidance literature:: With sodium hydride; In N,N-dimethyl-formamide; at 70 ℃; for 2h;
DOI:10.1248/cpb.30.3580

Reference yield:

: 85010-82-8
4-aniline

: 85010-84-0
5-<4-benzyl>thiazolidine-2,4-dione

Guidance literature:: Multi-step reaction with 2 steps

1: 1.) NaNO₂, conc. HCl, 2.) Cu₂O / 1.) acetone, MeOH, water, 5 deg C, 15 min, 2.) acetone, water, 35 deg C

2: 2.) 1N HCl / 1.) sulfolane, 110 deg C, 16 h; 2.) sulfolane, reflux, 8 h

With copper(I) oxide; hydrogenchloride; sodium nitrite;
DOI:10.1248/cpb.30.3580

Reference yield:

: 85010-82-8
4-aniline

: 85002-43-3
5-(4-phenethylaminobenzyl)thiazolidine-2,4-dione hydrochloride

Guidance literature:: Multi-step reaction with 3 steps

1: 1.) NaNO₂, conc. HCl, 2.) Cu₂O / 1.) acetone, MeOH, water, 5 deg C, 15 min, 2.) acetone, water, 35 deg C

2: 2.) 1N HCl / 1.) sulfolane, 110 deg C, 16 h; 2.) sulfolane, reflux, 8 h

3: 1.) conc. H₂SO₄; 2.) HCl / 1.) AcOH, 100 deg C, 1 h; 2.) Et₂O

With copper(I) oxide; hydrogenchloride; sulfuric acid; sodium nitrite;
DOI:10.1248/cpb.30.3580