N-Methyl-N-[(5-methyl-2-phenyl-1,3-oxazol-4-yl)methyl]amine

Base Information

Chemical Name:N-Methyl-N-[(5-methyl-2-phenyl-1,3-oxazol-4-yl)methyl]amine
CAS No.:132451-29-7
Molecular Formula:C12H14 N2 O
Molecular Weight:202.25
Hs Code.:2934999090
DSSTox Substance ID:DTXSID50575773
Wikidata:Q82465192
Mol file:132451-29-7.mol

Synonyms:132451-29-7;N-Methyl-N-[(5-methyl-2-phenyl-1,3-oxazol-4-yl)methyl]amine;N-Methyl-1-(5-methyl-2-phenyl-1,3-oxazol-4-yl)methanamine;4-Oxazolemethanamine, N,5-dimethyl-2-phenyl-;4-Oxazolemethanamine,N,5-dimethyl-2-phenyl-;SCHEMBL9316924;DTXSID50575773;AKOS002027585;CCG-185136

Suppliers and Price of N-Methyl-N-[(5-methyl-2-phenyl-1,3-oxazol-4-yl)methyl]amine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

American Custom Chemicals Corporation
N-METHYL-N-[(5-METHYL-2-PHENYL-1,3-OXAZOL-4-YL)METHYL]AMINE 95.00%
1G
$ 1260.24

Total 8 raw suppliers

Chemical Property of N-Methyl-N-[(5-methyl-2-phenyl-1,3-oxazol-4-yl)methyl]amine

Chemical Property:

Vapor Pressure:0.000181mmHg at 25°C
Boiling Point:329.1°Cat760mmHg
Flash Point:152.9°C
PSA：38.06000
Density:1.072g/cm³
LogP:2.76030
XLogP3:1.8
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:3
Exact Mass:202.110613074
Heavy Atom Count:15
Complexity:192

Purity/Quality:

98%min ^*data from raw suppliers

N-METHYL-N-[(5-METHYL-2-PHENYL-1,3-OXAZOL-4-YL)METHYL]AMINE 95.00% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC1=C(N=C(O1)C2=CC=CC=C2)CNC

Technology Process of N-Methyl-N-[(5-methyl-2-phenyl-1,3-oxazol-4-yl)methyl]amine

There total 7 articles about N-Methyl-N-[(5-methyl-2-phenyl-1,3-oxazol-4-yl)methyl]amine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: ethyl 5-methyl-3-oxo-2-phenyloxazole-4-carboxylate hydrochloride

: 132451-29-7
N-methyl-N-[(5-methyl-2-phenyl-4-oxazolyl)-methyl]amine

Guidance literature:: Multi-step reaction with 5 steps

1: 40 percent / H₂ / 10percent Pd/C / ethanol; methanol / 3 h / 2585.7 Torr

2: 84 percent / LiAlH₄ / diethyl ether / 1 h / Ambient temperature

3: 70 percent / pyridinium dichromate / CH₂Cl₂ / 7 h

4: MgSO₄ / diethyl ether / 1.) 0 deg C, 15 min, 2.) RT, 3 h

5: sodium borohydride / diethyl ether / 1.) 0 deg C, 15 min, 2.) RT, 18 h

With sodium tetrahydroborate; lithium aluminium tetrahydride; dipyridinium dichromate; hydrogen; magnesium sulfate; palladium on activated charcoal; In methanol; diethyl ether; ethanol; dichloromethane;
DOI:10.1021/jm00088a022

Reference yield:

: Methyl-[1-(5-methyl-2-phenyl-oxazol-4-yl)-meth-(E)-ylidene]-amine

: 132451-29-7
N-methyl-N-[(5-methyl-2-phenyl-4-oxazolyl)-methyl]amine

Guidance literature:: With sodium tetrahydroborate; In diethyl ether; Yield given; 1.) 0 deg C, 15 min, 2.) RT, 18 h;
DOI:10.1021/jm00088a022

Reference yield:

: 70502-03-3
[5-methyl-2-phenyl-1,3-oxazol-4-yl]methanol

: 132451-29-7
N-methyl-N-[(5-methyl-2-phenyl-4-oxazolyl)-methyl]amine

Guidance literature:: Multi-step reaction with 3 steps

1: 70 percent / pyridinium dichromate / CH₂Cl₂ / 7 h

2: MgSO₄ / diethyl ether / 1.) 0 deg C, 15 min, 2.) RT, 3 h

3: sodium borohydride / diethyl ether / 1.) 0 deg C, 15 min, 2.) RT, 18 h

With sodium tetrahydroborate; dipyridinium dichromate; magnesium sulfate; In diethyl ether; dichloromethane;
DOI:10.1021/jm00088a022